22490

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) PhoH-LOG/-
Location 1408814..1411137 Replicon chromosome
Accession NC_009840
Organism Prochlorococcus marinus str. MIT 9215

Toxin (Protein)


Gene name PhoH Uniprot ID A8G6L9
Locus tag P9215_RS07775 Protein ID WP_012008284.1
Coordinates 1408814..1410205 (+) Length 464 a.a.

Antitoxin (Protein)


Gene name LOG Uniprot ID A8G6M0
Locus tag P9215_RS07780 Protein ID WP_012008285.1
Coordinates 1410253..1411137 (+) Length 295 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9215_RS07745 1404119..1404595 - 477 WP_012008274.1 hypothetical protein -
P9215_RS07750 1404792..1405172 + 381 WP_012008275.1 DoxX family protein -
P9215_RS07755 1405192..1405395 - 204 WP_041484414.1 hypothetical protein -
P9215_RS07760 1405674..1406060 + 387 WP_041484415.1 DUF3804 family protein -
P9215_RS07765 1407561..1407818 + 258 WP_041484416.1 hypothetical protein -
P9215_RS10275 1408021..1408167 + 147 WP_012008282.1 hypothetical protein -
P9215_RS07770 1408249..1408767 + 519 WP_012008283.1 hypothetical protein -
P9215_RS07775 1408814..1410205 + 1392 WP_012008284.1 PhoH family protein Toxin
P9215_RS07780 1410253..1411137 + 885 WP_012008285.1 LOG family protein Antitoxin
P9215_RS07785 1411404..1411547 - 144 WP_012008286.1 high light inducible protein -
P9215_RS07790 1411547..1411663 - 117 WP_012008287.1 high light inducible protein -
P9215_RS07795 1411972..1412187 - 216 WP_012008289.1 hypothetical protein -
P9215_RS07800 1412539..1412874 + 336 WP_012008290.1 hypothetical protein -
P9215_RS10280 1412901..1413056 + 156 WP_002805975.1 hypothetical protein -
P9215_RS07805 1413053..1413481 + 429 WP_012008291.1 hypothetical protein -
P9215_RS07810 1413817..1414068 + 252 WP_012008292.1 hypothetical protein -
P9215_RS10285 1414109..1414267 + 159 WP_012008293.1 hypothetical protein -
P9215_RS07820 1414490..1414867 + 378 WP_012008294.1 hypothetical protein -
P9215_RS09935 1415071..1415172 + 102 WP_158508104.1 photosystem I reaction center subunit XII -
P9215_RS07830 1415571..1415801 - 231 WP_012008296.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-150)

Antitoxin

(157-285)


Sequences


Toxin        


Download         Length: 464 a.a.        Molecular weight: 52082.54 Da        Isoelectric Point: 8.0787

>T22490 WP_012008284.1 NC_009840:1408814-1410205 [Prochlorococcus marinus str. MIT 9215]
MKKRVIVLDTNVLLHDPESPLHFANENVVIPIQVVEEVDRFKRDPGEKGRNARRFSRLLDSLREKGNLSSGAKINNKFEG
TIKVAFCRKETTDRLPLELNDSSGDNKILAVALEEKNTKILSDFPEVVLISKDTNMRIKADAVGLKAEDYYKDKISLENL
EKGFREISSNSDEINKVQKDGFIYLRDIKSKFEPSLVSNEGVILKDNLKENHTFLTRYNQSEKKLVGLNHLRRSNLGKVK
PKNLEQNFALDLLLDPKVQLVSLVGKAGTGKTLLALAVGLHQVADENIYERLLVSRPPIPLGKELGYLPGSLDEKLAPWM
KPIIDNLDYLTSPKTNKNGEKNDRKERDNHSKNSWEDLRGMGLLEVEAINYIRGRSITNQFILIDEAQNLTPLEVKTIVT
RAGEGTKIVFTGDPNQIDHPYLDSDSNGLTWLAKKLHGQKIIGHITLSQGERSDLAELAADLL

Download         Length: 1392 bp

>T22490 NC_009840:1408814-1410205 [Prochlorococcus marinus str. MIT 9215]
ATGAAAAAAAGAGTTATTGTTCTTGACACAAATGTCTTATTACATGATCCAGAATCACCTCTTCATTTTGCTAATGAAAA
TGTTGTAATCCCAATTCAAGTAGTTGAAGAGGTTGATAGATTCAAACGCGATCCTGGAGAGAAAGGTCGCAATGCCAGAA
GATTTTCTAGACTACTAGATAGTCTTCGAGAAAAAGGTAATCTATCTTCAGGTGCAAAAATTAATAATAAATTTGAAGGG
ACAATAAAAGTTGCATTTTGCAGAAAAGAGACAACTGATAGATTGCCCTTAGAACTAAATGATAGTAGTGGAGATAATAA
AATTTTAGCTGTCGCTCTTGAAGAAAAAAATACCAAAATCTTATCAGACTTTCCAGAAGTAGTACTTATTTCAAAAGATA
CAAATATGCGAATCAAGGCTGATGCAGTTGGTCTCAAAGCGGAAGATTATTATAAAGACAAGATTTCTTTAGAAAATTTA
GAAAAAGGTTTTAGGGAAATAAGTTCCAATTCAGATGAGATAAATAAGGTTCAAAAAGATGGGTTTATTTATTTAAGAGA
TATTAAATCAAAATTTGAACCATCTTTAGTAAGTAATGAGGGTGTAATCTTAAAAGATAATTTAAAAGAAAATCATACTT
TTTTAACTAGATATAATCAATCTGAGAAAAAGTTAGTAGGTCTTAATCACTTAAGAAGATCAAATTTAGGTAAAGTCAAA
CCTAAGAATCTTGAACAAAATTTTGCTTTAGATTTGCTACTTGATCCAAAAGTTCAATTAGTAAGTCTTGTCGGAAAAGC
AGGAACAGGAAAAACTTTACTTGCTTTGGCCGTTGGACTACATCAAGTTGCAGATGAAAACATTTACGAAAGATTATTAG
TATCTAGACCACCAATACCTTTAGGAAAAGAATTAGGTTATCTGCCAGGTAGTCTTGATGAGAAATTAGCTCCTTGGATG
AAACCAATTATTGATAATTTAGATTATCTAACAAGTCCAAAAACGAACAAAAATGGAGAAAAAAATGATCGTAAAGAAAG
AGATAATCACTCTAAAAACTCATGGGAAGATTTGAGAGGTATGGGTCTACTGGAAGTAGAAGCAATAAATTACATTAGAG
GAAGATCAATTACTAATCAATTCATTCTTATTGATGAAGCACAAAATTTAACACCTTTAGAAGTTAAAACTATTGTTACC
AGAGCAGGAGAAGGAACTAAGATTGTTTTTACGGGCGATCCAAATCAAATAGATCATCCTTATCTTGATTCTGATAGTAA
TGGTTTGACTTGGTTAGCAAAAAAATTGCATGGACAAAAAATAATTGGACACATCACTTTATCTCAAGGAGAAAGAAGTG
ATTTAGCAGAATTAGCAGCGGATCTTTTATAG

Antitoxin


Download         Length: 295 a.a.        Molecular weight: 33039.16 Da        Isoelectric Point: 9.4531

>AT22490 WP_012008285.1 NC_009840:1410253-1411137 [Prochlorococcus marinus str. MIT 9215]
MKDKFKCNFAKERSNEVELVASNLEAILKSSTYKLAHEDIDLLNTDEMRGVRMLLEITKPEQVLEKEKIISTVIVFGGVH
ISEEIASKRRVDDAVKLLSKNPNSKSLKITIEKLKNLHSLSHYYSSARELSKLISLDSKTKSSNSHVIVTGGGPGIMEAA
NRGAFDAGCKSIGLNISLPNEQHPNSFITPGLCFKFNYFAMRKFHFVMRSTSAVFFPGGFGTLDELFELLTLRQTNMKGK
IPIILFGRSYWEKVINFQFLSDMGLIGENDLSIFQYADTANEAWNLIKQSSKKL

Download         Length: 885 bp

>AT22490 NC_009840:1410253-1411137 [Prochlorococcus marinus str. MIT 9215]
ATGAAAGACAAATTTAAATGTAATTTTGCAAAAGAAAGAAGTAACGAGGTTGAATTAGTTGCTAGTAATTTAGAAGCAAT
TTTAAAATCTAGTACTTATAAACTTGCTCACGAAGATATAGATTTATTGAATACTGATGAAATGAGAGGGGTGAGGATGC
TCCTTGAAATAACAAAGCCTGAGCAGGTACTCGAGAAAGAAAAGATAATTTCAACTGTAATTGTTTTTGGAGGTGTCCAC
ATATCCGAAGAGATTGCATCCAAAAGAAGGGTCGATGATGCGGTCAAACTTCTTTCAAAAAATCCCAACTCTAAATCTTT
AAAGATCACTATCGAGAAATTAAAAAATTTGCACTCCCTCTCACATTATTATTCTTCAGCGAGAGAGTTATCTAAATTAA
TCTCGCTAGATAGCAAAACAAAAAGTTCCAATTCGCATGTAATAGTTACTGGTGGAGGACCAGGGATTATGGAAGCAGCT
AACAGAGGAGCATTTGATGCTGGCTGCAAGTCTATTGGATTAAACATAAGCCTACCAAATGAGCAACACCCTAATTCTTT
TATCACACCAGGATTATGTTTTAAATTTAATTATTTTGCCATGAGGAAATTTCATTTCGTTATGAGATCTACTTCTGCAG
TTTTTTTTCCAGGAGGATTTGGAACTTTAGATGAATTATTTGAATTATTAACATTAAGACAGACCAACATGAAGGGGAAA
ATTCCAATAATCTTATTTGGCAGAAGCTATTGGGAAAAGGTAATAAATTTTCAATTTTTATCTGATATGGGGTTAATTGG
AGAGAATGATTTGTCTATTTTTCAATACGCTGATACAGCAAATGAAGCTTGGAATTTAATAAAACAAAGTAGCAAAAAGC
TTTAG

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A8G6L9


Antitoxin

Source ID Structure
AlphaFold DB A8G6M0

References