Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2008259..2008404 Replicon chromosome
Accession NZ_CP087146
Organism Klebsiella pneumoniae strain KP16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2008295..2008397 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2008259..2008404 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOX92_RS09825 (LOX92_09825) 2003389..2005449 + 2061 WP_004151449.1 oligopeptidase B -
LOX92_RS09830 (LOX92_09830) 2005453..2006112 - 660 WP_002911407.1 exodeoxyribonuclease X -
LOX92_RS09835 (LOX92_09835) 2006191..2006421 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOX92_RS09840 (LOX92_09840) 2006534..2006908 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOX92_RS09845 (LOX92_09845) 2006912..2007781 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LOX92_RS09850 (LOX92_09850) 2007798..2008136 + 339 WP_002911404.1 YebY family protein -
- 2008259..2008404 - 146 - - Antitoxin
- 2008295..2008397 + 103 - - Toxin
LOX92_RS09855 (LOX92_09855) 2008772..2008915 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOX92_RS09860 (LOX92_09860) 2009020..2009988 - 969 WP_004151446.1 VirK/YbjX family protein -
LOX92_RS09865 (LOX92_09865) 2010145..2010798 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LOX92_RS09870 (LOX92_09870) 2010795..2010986 - 192 WP_002911395.1 YebW family protein -
LOX92_RS09875 (LOX92_09875) 2011084..2011323 - 240 WP_002911393.1 YebV family protein -
LOX92_RS09880 (LOX92_09880) 2011439..2012872 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T224893 NZ_CP087146:2008295-2008397 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT224893 NZ_CP087146:c2008404-2008259 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References