224866

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010269..2010414 Replicon chromosome
Accession NZ_CP087142
Organism Klebsiella pneumoniae strain KP15

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010305..2010407 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010269..2010414 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOX91_RS09835 (LOX91_09835) 2005399..2007459 + 2061 WP_004151449.1 oligopeptidase B -
LOX91_RS09840 (LOX91_09840) 2007463..2008122 - 660 WP_002911407.1 exodeoxyribonuclease X -
LOX91_RS09845 (LOX91_09845) 2008201..2008431 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOX91_RS09850 (LOX91_09850) 2008544..2008918 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOX91_RS09855 (LOX91_09855) 2008922..2009791 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
LOX91_RS09860 (LOX91_09860) 2009808..2010146 + 339 WP_002911404.1 YebY family protein -
- 2010269..2010414 - 146 - - Antitoxin
- 2010305..2010407 + 103 - - Toxin
LOX91_RS09865 (LOX91_09865) 2010782..2010925 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOX91_RS09870 (LOX91_09870) 2011030..2011998 - 969 WP_004151446.1 VirK/YbjX family protein -
LOX91_RS09875 (LOX91_09875) 2012155..2012808 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LOX91_RS09880 (LOX91_09880) 2012805..2012996 - 192 WP_002911395.1 YebW family protein -
LOX91_RS09885 (LOX91_09885) 2013094..2013333 - 240 WP_002911393.1 YebV family protein -
LOX91_RS09890 (LOX91_09890) 2013449..2014882 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T224866 NZ_CP087142:2010305-2010407 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT224866 NZ_CP087142:c2010414-2010269 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References