Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1(toxin) |
Location | 3589834..3590417 | Replicon | chromosome |
Accession | NZ_CP087138 | ||
Organism | Pseudomonas sp. KNUC1026 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | LN139_RS16850 | Protein ID | WP_236355297.1 |
Coordinates | 3589834..3590199 (-) | Length | 122 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | LN139_RS16855 | Protein ID | WP_236355298.1 |
Coordinates | 3590193..3590417 (-) | Length | 75 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LN139_RS16840 (LN139_16840) | 3585636..3588670 | - | 3035 | Protein_3347 | FAD-binding and (Fe-S)-binding domain-containing protein | - |
LN139_RS16845 (LN139_16845) | 3588825..3589697 | + | 873 | WP_236355296.1 | LysR substrate-binding domain-containing protein | - |
LN139_RS16850 (LN139_16850) | 3589834..3590199 | - | 366 | WP_236355297.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
LN139_RS16855 (LN139_16855) | 3590193..3590417 | - | 225 | WP_236355298.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
LN139_RS16860 (LN139_16860) | 3590503..3591660 | - | 1158 | WP_236360471.1 | MFS transporter | - |
LN139_RS16865 (LN139_16865) | 3591821..3593878 | - | 2058 | WP_236355299.1 | HAMP domain-containing methyl-accepting chemotaxis protein | - |
LN139_RS16875 (LN139_16875) | 3594287..3594961 | + | 675 | WP_236355300.1 | two-component system response regulator CreB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 122 a.a. Molecular weight: 13428.80 Da Isoelectric Point: 7.0122
>T224861 WP_236355297.1 NZ_CP087138:c3590199-3589834 [Pseudomonas sp. KNUC1026]
MVKLLYGANILIDYLNGIVPAQLELDKAANPMISVITWMEVMAGTSAAEEGDIRAWLETFQLIRLDSKIADVAVSIRKLR
RIKLPDAIVWASAKAHSAVLVSRNVKDFPPQEADVRVPYLL
MVKLLYGANILIDYLNGIVPAQLELDKAANPMISVITWMEVMAGTSAAEEGDIRAWLETFQLIRLDSKIADVAVSIRKLR
RIKLPDAIVWASAKAHSAVLVSRNVKDFPPQEADVRVPYLL
Download Length: 366 bp
>T224861 NZ_CP120567:3069116-3069223 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8485.61 Da Isoelectric Point: 5.8150
>AT224861 WP_236355298.1 NZ_CP087138:c3590417-3590193 [Pseudomonas sp. KNUC1026]
MARILVDLPDDQLESLATIGAREMRPRAALIRDAVAQYLSSHRSAEQTSAKVFGLWRDRAVDGVKYQQELREEW
MARILVDLPDDQLESLATIGAREMRPRAALIRDAVAQYLSSHRSAEQTSAKVFGLWRDRAVDGVKYQQELREEW
Download Length: 225 bp
>AT224861 NZ_CP120567:c3069063-3069002 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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