Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | VII | Classification (family/domain) | HepT-MntA/HepT(toxin) |
Location | 2400483..2401287 | Replicon | chromosome |
Accession | NZ_CP087138 | ||
Organism | Pseudomonas sp. KNUC1026 |
Toxin (Protein)
Gene name | hepT | Uniprot ID | - |
Locus tag | LN139_RS11045 | Protein ID | WP_236359909.1 |
Coordinates | 2400483..2400899 (-) | Length | 139 a.a. |
Antitoxin (Protein)
Gene name | mntA | Uniprot ID | - |
Locus tag | LN139_RS11050 | Protein ID | WP_236359910.1 |
Coordinates | 2400892..2401287 (-) | Length | 132 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LN139_RS11030 (LN139_11030) | 2395771..2397806 | - | 2036 | Protein_2190 | alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase | - |
LN139_RS11035 (LN139_11035) | 2398190..2399326 | + | 1137 | WP_236359908.1 | enoyl-CoA hydratase/isomerase family protein | - |
LN139_RS11040 (LN139_11040) | 2399352..2400485 | + | 1134 | Protein_2192 | acyl-CoA dehydrogenase family protein | - |
LN139_RS11045 (LN139_11045) | 2400483..2400899 | - | 417 | WP_236359909.1 | DUF86 domain-containing protein | Toxin |
LN139_RS11050 (LN139_11050) | 2400892..2401287 | - | 396 | WP_236359910.1 | nucleotidyltransferase domain-containing protein | Antitoxin |
LN139_RS11055 (LN139_11055) | 2401348..2402094 | - | 747 | WP_236359911.1 | IclR family transcriptional regulator | - |
LN139_RS11060 (LN139_11060) | 2402165..2403678 | + | 1514 | Protein_2196 | MFS transporter | - |
LN139_RS11065 (LN139_11065) | 2403766..2404704 | + | 939 | WP_236359912.1 | HlyD family secretion protein | - |
LN139_RS11070 (LN139_11070) | 2404708..2406111 | + | 1404 | WP_236359913.1 | efflux transporter outer membrane subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 139 a.a. Molecular weight: 15846.19 Da Isoelectric Point: 6.8531
>T224860 WP_236359909.1 NZ_CP087138:c2400899-2400483 [Pseudomonas sp. KNUC1026]
MDDDVLINKAATVERCVARAREEYAKNPDTFATDFTRQDAAILNLQRACQASLDMGQHVVRMRKLGIPQRYQDVFTFLEQ
AQLIDQPLSDSMKRMCGFRNIAVHEYQKVQLPITVAIIKHDLDDFTTFTRTLPPLPPH
MDDDVLINKAATVERCVARAREEYAKNPDTFATDFTRQDAAILNLQRACQASLDMGQHVVRMRKLGIPQRYQDVFTFLEQ
AQLIDQPLSDSMKRMCGFRNIAVHEYQKVQLPITVAIIKHDLDDFTTFTRTLPPLPPH
Download Length: 417 bp
>T224860 NZ_CP120567:2825964-2826242 [Escherichia coli]
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCATGCTGTCTTGCTGATATCGATATGCCCGGTTACCGATTAC
ATCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGCAACTGGCGAATCACATTTGAATTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCATGCTGTCTTGCTGATATCGATATGCCCGGTTACCGATTAC
ATCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGCAACTGGCGAATCACATTTGAATTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA
Antitoxin
Download Length: 132 a.a. Molecular weight: 14772.91 Da Isoelectric Point: 4.9185
>AT224860 WP_236359910.1 NZ_CP087138:c2401287-2400892 [Pseudomonas sp. KNUC1026]
MDLPLILGTLERHLPNWQAFYLFGSHAHGTDRPDSDLDLAVLCDGPPLDPVRMWEIAQIVAEVARCDVDLIDLKSASTVL
QWQIVVHGERLKARQPLTGDFEAKVVQQKFELDALRARQLKDIRENGSVYG
MDLPLILGTLERHLPNWQAFYLFGSHAHGTDRPDSDLDLAVLCDGPPLDPVRMWEIAQIVAEVARCDVDLIDLKSASTVL
QWQIVVHGERLKARQPLTGDFEAKVVQQKFELDALRARQLKDIRENGSVYG
Download Length: 396 bp
>AT224860 NZ_CP120567:2826242-2826526 [Escherichia coli]
ATGAAAATGGCCAATCATCCCCGCCCGGGGGACATTATTCAGGAATCACTGGACGAACTTAATGTCAGCCTGCGCGAGTT
TGCCAGAGCAATGGAAATTGCGCCCTCAACGGCAAGCCGATTGCTGACCGGAAAAGCAGCTTTGACGCCAGAAATGGCAA
TAAAACTTTCCGTGGTGATCGGCAGTTCGCCGCAAATGTGGCTGAATCTGCAAAATGCCTGGAGTCTGGCAGAGGCTGAA
AAAACGGTGGATGTGTCGCGACTGCGCCGTCTGGTTACGCAATAA
ATGAAAATGGCCAATCATCCCCGCCCGGGGGACATTATTCAGGAATCACTGGACGAACTTAATGTCAGCCTGCGCGAGTT
TGCCAGAGCAATGGAAATTGCGCCCTCAACGGCAAGCCGATTGCTGACCGGAAAAGCAGCTTTGACGCCAGAAATGGCAA
TAAAACTTTCCGTGGTGATCGGCAGTTCGCCGCAAATGTGGCTGAATCTGCAAAATGCCTGGAGTCTGGCAGAGGCTGAA
AAAACGGTGGATGTGTCGCGACTGCGCCGTCTGGTTACGCAATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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