Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2400483..2401287 Replicon chromosome
Accession NZ_CP087138
Organism Pseudomonas sp. KNUC1026

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag LN139_RS11045 Protein ID WP_236359909.1
Coordinates 2400483..2400899 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag LN139_RS11050 Protein ID WP_236359910.1
Coordinates 2400892..2401287 (-) Length 132 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN139_RS11030 (LN139_11030) 2395771..2397806 - 2036 Protein_2190 alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase -
LN139_RS11035 (LN139_11035) 2398190..2399326 + 1137 WP_236359908.1 enoyl-CoA hydratase/isomerase family protein -
LN139_RS11040 (LN139_11040) 2399352..2400485 + 1134 Protein_2192 acyl-CoA dehydrogenase family protein -
LN139_RS11045 (LN139_11045) 2400483..2400899 - 417 WP_236359909.1 DUF86 domain-containing protein Toxin
LN139_RS11050 (LN139_11050) 2400892..2401287 - 396 WP_236359910.1 nucleotidyltransferase domain-containing protein Antitoxin
LN139_RS11055 (LN139_11055) 2401348..2402094 - 747 WP_236359911.1 IclR family transcriptional regulator -
LN139_RS11060 (LN139_11060) 2402165..2403678 + 1514 Protein_2196 MFS transporter -
LN139_RS11065 (LN139_11065) 2403766..2404704 + 939 WP_236359912.1 HlyD family secretion protein -
LN139_RS11070 (LN139_11070) 2404708..2406111 + 1404 WP_236359913.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(22-131)

Antitoxin

Polymerase beta, nucleotidyltransferase

(12-95)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15846.19 Da        Isoelectric Point: 6.8531

>T224860 WP_236359909.1 NZ_CP087138:c2400899-2400483 [Pseudomonas sp. KNUC1026]
MDDDVLINKAATVERCVARAREEYAKNPDTFATDFTRQDAAILNLQRACQASLDMGQHVVRMRKLGIPQRYQDVFTFLEQ
AQLIDQPLSDSMKRMCGFRNIAVHEYQKVQLPITVAIIKHDLDDFTTFTRTLPPLPPH

Download         Length: 417 bp

>T224860 NZ_CP120567:2825964-2826242 [Escherichia coli]
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCATGCTGTCTTGCTGATATCGATATGCCCGGTTACCGATTAC
ATCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGCAACTGGCGAATCACATTTGAATTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA

Antitoxin


Download         Length: 132 a.a.        Molecular weight: 14772.91 Da        Isoelectric Point: 4.9185

>AT224860 WP_236359910.1 NZ_CP087138:c2401287-2400892 [Pseudomonas sp. KNUC1026]
MDLPLILGTLERHLPNWQAFYLFGSHAHGTDRPDSDLDLAVLCDGPPLDPVRMWEIAQIVAEVARCDVDLIDLKSASTVL
QWQIVVHGERLKARQPLTGDFEAKVVQQKFELDALRARQLKDIRENGSVYG

Download         Length: 396 bp

>AT224860 NZ_CP120567:2826242-2826526 [Escherichia coli]
ATGAAAATGGCCAATCATCCCCGCCCGGGGGACATTATTCAGGAATCACTGGACGAACTTAATGTCAGCCTGCGCGAGTT
TGCCAGAGCAATGGAAATTGCGCCCTCAACGGCAAGCCGATTGCTGACCGGAAAAGCAGCTTTGACGCCAGAAATGGCAA
TAAAACTTTCCGTGGTGATCGGCAGTTCGCCGCAAATGTGGCTGAATCTGCAAAATGCCTGGAGTCTGGCAGAGGCTGAA
AAAACGGTGGATGTGTCGCGACTGCGCCGTCTGGTTACGCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References