Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2507704..2508212 Replicon chromosome
Accession NZ_CP087124
Organism Sulfurovum sp. HSL1-3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LN246_RS12800 Protein ID WP_229937104.1
Coordinates 2507704..2507964 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LN246_RS12805 Protein ID WP_229937105.1
Coordinates 2507961..2508212 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN246_RS12780 (LN246_12780) 2504104..2505174 - 1071 WP_229937100.1 GGDEF domain-containing protein -
LN246_RS12785 (LN246_12785) 2505733..2506008 - 276 WP_229937101.1 type II toxin-antitoxin system RelE/ParE family toxin -
LN246_RS12790 (LN246_12790) 2505998..2506264 - 267 WP_229937102.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
LN246_RS12795 (LN246_12795) 2506568..2506729 - 162 WP_229937103.1 hypothetical protein -
LN246_RS12800 (LN246_12800) 2507704..2507964 - 261 WP_229937104.1 Txe/YoeB family addiction module toxin Toxin
LN246_RS12805 (LN246_12805) 2507961..2508212 - 252 WP_229937105.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LN246_RS12810 (LN246_12810) 2508889..2510394 - 1506 WP_229937106.1 hypothetical protein -
LN246_RS12815 (LN246_12815) 2510743..2511108 + 366 WP_229937107.1 four helix bundle protein -
LN246_RS12820 (LN246_12820) 2511292..2512731 + 1440 WP_229937108.1 nucleotidyltransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10455.96 Da        Isoelectric Point: 9.3595

>T224812 WP_229937104.1 NZ_CP087124:c2507964-2507704 [Sulfurovum sp. HSL1-3]
MIIGFADRGWEDYQYWVHNDKKIVKRINLLLQDIKRNPDDSNGLGRPERLKENFQGYFSRRITSEHRLVYKIIEDIIVVA
QCRYHY

Download         Length: 261 bp

>T224812 NZ_CP120557:2477566-2477940 [Escherichia coli]
ATGAAAACATTACCCGATACACACGTACGGGAGGCATCGAGCTGCCCGTCTCCCGTCACCATCTGGCAGACTCTGCTCTC
CCGACTACTGGGCCAGCATTACGGCCTTACACTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACTTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGCATCCGGAGAAACGATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9717.98 Da        Isoelectric Point: 4.4692

>AT224812 WP_229937105.1 NZ_CP087124:c2508212-2507961 [Sulfurovum sp. HSL1-3]
MQAVFYSQARNNLRDIINKVCDDFDEYIITTKDNKSAVILSYEEYSAMKETMYLLASKNNRERLNDAVEQIENAAFIKKD
IEL

Download         Length: 252 bp

>AT224812 NZ_CP120557:2477108-2477476 [Escherichia coli]
GTGTCAGACGCACTCTCCGGGACAATGCTTCCCGACGACAATCACGACCGCCCCTGGTGGGGGCTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGGAGGGTAACCGCCTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCTGT
TCAGCGATGCAGATGCGTACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTCACGCTGTATGCAAAAGGTCTGACCTGCAAAGCTGACACTCTCGGTAGCGG
TGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References