Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2075656..2075801 Replicon chromosome
Accession NZ_CP087123
Organism Klebsiella pneumoniae strain TH12908

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2075692..2075794 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2075656..2075801 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOX65_RS10005 2070786..2072846 + 2061 WP_004151449.1 oligopeptidase B -
LOX65_RS10010 2072850..2073509 - 660 WP_002911407.1 exodeoxyribonuclease X -
LOX65_RS10015 2073588..2073818 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOX65_RS10020 2073931..2074305 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOX65_RS10025 2074309..2075178 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
LOX65_RS10030 2075195..2075533 + 339 WP_002911404.1 YebY family protein -
- 2075656..2075801 - 146 - - Antitoxin
- 2075692..2075794 + 103 - - Toxin
LOX65_RS10035 2076169..2076312 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOX65_RS10040 2076417..2077385 - 969 WP_014907334.1 VirK/YbjX family protein -
LOX65_RS10045 2077542..2078195 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
LOX65_RS10050 2078192..2078383 - 192 WP_002911395.1 YebW family protein -
LOX65_RS10055 2078481..2078720 - 240 WP_002911393.1 YebV family protein -
LOX65_RS10060 2078836..2080269 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T224795 NZ_CP087123:2075692-2075794 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT224795 NZ_CP087123:c2075801-2075656 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References