Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1860684..1860829 Replicon chromosome
Accession NZ_CP087122
Organism Klebsiella pneumoniae strain TH12852

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1860720..1860822 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1860684..1860829 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOX64_RS09090 1855814..1857874 + 2061 WP_004151449.1 oligopeptidase B -
LOX64_RS09095 1857878..1858537 - 660 WP_002911407.1 exodeoxyribonuclease X -
LOX64_RS09100 1858616..1858846 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOX64_RS09105 1858959..1859333 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOX64_RS09110 1859337..1860206 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LOX64_RS09115 1860223..1860561 + 339 WP_016529031.1 YebY family protein -
- 1860684..1860829 - 146 - - Antitoxin
- 1860720..1860822 + 103 - - Toxin
LOX64_RS09120 1861197..1861340 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOX64_RS09125 1861445..1862413 - 969 WP_167875849.1 VirK/YbjX family protein -
LOX64_RS09130 1862570..1863223 + 654 WP_016529030.1 protein-serine/threonine phosphatase -
LOX64_RS09135 1863220..1863411 - 192 WP_002911395.1 YebW family protein -
LOX64_RS09140 1863509..1863748 - 240 WP_002911393.1 YebV family protein -
LOX64_RS09145 1863864..1865297 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T224770 NZ_CP087122:1860720-1860822 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT224770 NZ_CP087122:c1860829-1860684 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References