Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3811739..3812204 Replicon chromosome
Accession NZ_CP087002
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-105

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE06_RS19030 Protein ID WP_224557762.1
Coordinates 3811739..3812002 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE06_RS19035 Protein ID WP_224557764.1
Coordinates 3811989..3812204 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE06_RS19005 (LOE06_19005) 3807457..3809007 - 1551 WP_224557015.1 restriction endonuclease subunit S -
LOE06_RS19010 (LOE06_19010) 3809004..3809300 - 297 WP_224557153.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
LOE06_RS19015 (LOE06_19015) 3809194..3809682 - 489 WP_229938596.1 DEAD/DEAH box helicase family protein -
LOE06_RS19020 (LOE06_19020) 3809907..3811015 - 1109 Protein_3755 IS110 family transposase -
LOE06_RS19025 (LOE06_19025) 3811108..3811551 - 444 WP_224557760.1 hypothetical protein -
LOE06_RS19030 (LOE06_19030) 3811739..3812002 + 264 WP_224557762.1 BrnT family toxin Toxin
LOE06_RS19035 (LOE06_19035) 3811989..3812204 + 216 WP_224557764.1 CopG family antitoxin Antitoxin
LOE06_RS19040 (LOE06_19040) 3812557..3812781 - 225 WP_224557765.1 hypothetical protein -
LOE06_RS19045 (LOE06_19045) 3812949..3813329 - 381 WP_224557766.1 helix-turn-helix domain-containing protein -
LOE06_RS19050 (LOE06_19050) 3813510..3814481 - 972 WP_224557767.1 hypothetical protein -
LOE06_RS19055 (LOE06_19055) 3814474..3815658 - 1185 WP_224557768.1 site-specific integrase -
LOE06_RS19065 (LOE06_19065) 3816036..3816734 - 699 WP_037931342.1 SURF1 family protein -
LOE06_RS19070 (LOE06_19070) 3816731..3817096 - 366 WP_028957811.1 cytochrome o ubiquinol oxidase subunit IV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3803147..3815658 12511


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10254.52 Da        Isoelectric Point: 5.6550

>T224642 WP_224557762.1 NZ_CP087002:3811739-3812002 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Download         Length: 264 bp

>T224642 NZ_CP120376:c2638620-2638435 [Pseudomonas nitroreducens]
ATCCGCTCGATGGGCATCGGTGTCTCGGAAATCCGACTGGATGTCGGCCCTGGCTATTGCGTCTACTTCAGGCGCCGTGG
CGACGTGCCGATCCTGTTGCTGTGTGGCGGCGAAAAAACATCCCAGCAGCGCGATATCAAGCTGGCGCAGCAACTGGCGG
GAGCAATTGAATGGCCATTGAACTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8265.40 Da        Isoelectric Point: 10.6538

>AT224642 WP_224557764.1 NZ_CP087002:3811989-3812204 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT224642 NZ_CP120376:c2638450-2638154 [Pseudomonas nitroreducens]
ATGGCCATTGAACTGAGCGACTTCGACACTAGCCACCACCTCGACAATGAGGAGGTCATTGCCGAATACCTGTCCCAGGT
CCTGTCTGACGGCGATACCGATGAGCTGCTACTCGCCATCGGCAACATTGCCAAGGCGCGCGGCATGACCAAGATCGCCA
ATGACTCGGGACTGGGCCGGGAGAGCCTGTACAAGGTCTTTGCGCCCGGAGCCAAGCCGCGCTTCGAGACGGTCATGAAG
GTCATGCGCGCGCTGGGTGTCGAGTTGCAGGCAATTCCCGCCAGCAGCGGGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References