Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 82356..83030 Replicon plasmid P7
Accession NZ_CP086993
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-110

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LOE08_RS23635 Protein ID WP_224557924.1
Coordinates 82356..82778 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LOE08_RS23640 Protein ID WP_229939240.1
Coordinates 82782..83030 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE08_RS23625 (LOE08_23575) 78554..79612 - 1059 WP_224557922.1 HEPN domain-containing protein -
LOE08_RS23630 (LOE08_23580) 79609..82359 - 2751 WP_224557923.1 lactate dehydrogenase -
LOE08_RS23635 (LOE08_23585) 82356..82778 - 423 WP_224557924.1 type II toxin-antitoxin system VapC family toxin Toxin
LOE08_RS23640 (LOE08_23590) 82782..83030 - 249 WP_229939240.1 plasmid stabilization protein Antitoxin
LOE08_RS23645 (LOE08_23595) 83178..84167 - 990 WP_224557926.1 P-type DNA transfer ATPase VirB11 -
LOE08_RS23650 (LOE08_23600) 84278..85735 - 1458 WP_224557927.1 TrbI/VirB10 family protein -
LOE08_RS23655 (LOE08_23605) 85738..86469 - 732 WP_224557928.1 TrbG/VirB9 family P-type conjugative transfer protein -
LOE08_RS23660 (LOE08_23610) 86473..87117 - 645 WP_224557929.1 type IV secretion system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..97224 97224


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15255.26 Da        Isoelectric Point: 4.3767

>T224632 WP_224557924.1 NZ_CP086993:c82778-82356 [Pseudosulfitobacter pseudonitzschiae]
MIILDTNVICELLRPTPEPRIEQWLSAQDGLNVYLTSISEAELRYGLANMGNGKRRAALIDAVDRILREDLAGRILPFDS
DAAQAYASIAATRRDAGRPIAQADCQIASIAHACGATVATRNTPDFEGCEIDLINPWTTE

Download         Length: 423 bp

>T224632 NZ_CP120370:c2206066-2205680 [Sinorhizobium numidicum]
ATGGTCATCGACACCTCCGCCATCGTCGCGATCGCATTCAATGAGCCGGAAGCGGAAAGCTACGAGCAAAAAGTCGTCGA
CGCTCCACGGCGCTTCATCTCGGCCGCGACAGTCCTTGAACTGGCAATCGTCATCGAGGCGCGCCTCGGCGAGGCAGGTG
CCGCCGAGCTCGATCTATGGCTCTACAAGGCGGGCGTCGAAATCGTCGCCGTCGACGCGGAGCAGATCGCCGTCGCAAGG
CGAGCCTGGCGCAGCTACGGCAAAGGCCGACATCCGGCAGGTCTGAATTATGGAGACTGTTTCTCCTATGCGCTGGCCAA
GACGCGCAACGAACCGCTGCTCTTCAAAGGTGATGATTTCTCACGCACCGACATGCAGGCGGCATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9206.46 Da        Isoelectric Point: 6.7281

>AT224632 WP_229939240.1 NZ_CP086993:c83030-82782 [Pseudosulfitobacter pseudonitzschiae]
MASITIRNLDDDVKRRLRIRAAEHGRSMEEEAREILRQVVGDAKPNHDLAAAIRARVGPLGGVELDLPQREAMHEPPTFD
RA

Download         Length: 249 bp

>AT224632 NZ_CP120370:c2206320-2206066 [Sinorhizobium numidicum]
ATGGCGCTCAGCATTAAAGATCTAGAGACGGAACGCCTGGCAAAGGCACTGGCCGAGAAGACTGGTGAAACTATTACCAT
GGCGACCCGCCGCGCACTGGAAGAGCGGCTGCGGCGTCTCGCAAACACGGGAAATCGCGATGTTCTTCTCGAGGAGCTTG
CCGCCAGCCGTCGACGCTGGGCGAAGCTGCCGGTGCTCGACAACCGCTCTGCCGATGAGATTTTGGGGTATGACGAAAAC
GGGCTCCCCAACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References