Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /BrnT(toxin) |
| Location | 3812477..3812942 | Replicon | chromosome |
| Accession | NZ_CP086954 | ||
| Organism | Pseudosulfitobacter pseudonitzschiae strain SC1-27 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LOE13_RS19055 | Protein ID | WP_224557762.1 |
| Coordinates | 3812477..3812740 (+) | Length | 88 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | LOE13_RS19060 | Protein ID | WP_224557764.1 |
| Coordinates | 3812727..3812942 (+) | Length | 72 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOE13_RS19030 (LOE13_19025) | 3808193..3809743 | - | 1551 | WP_224557015.1 | restriction endonuclease subunit S | - |
| LOE13_RS19035 (LOE13_19030) | 3809740..3810036 | - | 297 | WP_224557153.1 | type I restriction-modification enzyme R subunit C-terminal domain-containing protein | - |
| LOE13_RS19040 (LOE13_19035) | 3809930..3810418 | - | 489 | WP_229938596.1 | DEAD/DEAH box helicase family protein | - |
| LOE13_RS19045 (LOE13_19040) | 3810644..3811753 | - | 1110 | WP_224558030.1 | IS110 family transposase | - |
| LOE13_RS19050 (LOE13_19045) | 3811846..3812289 | - | 444 | WP_224557760.1 | hypothetical protein | - |
| LOE13_RS19055 (LOE13_19050) | 3812477..3812740 | + | 264 | WP_224557762.1 | BrnT family toxin | Toxin |
| LOE13_RS19060 (LOE13_19055) | 3812727..3812942 | + | 216 | WP_224557764.1 | CopG family antitoxin | Antitoxin |
| LOE13_RS19065 (LOE13_19060) | 3813295..3813519 | - | 225 | WP_224557765.1 | hypothetical protein | - |
| LOE13_RS19070 (LOE13_19065) | 3813687..3814067 | - | 381 | WP_224557766.1 | helix-turn-helix domain-containing protein | - |
| LOE13_RS19075 (LOE13_19070) | 3814248..3815219 | - | 972 | WP_224557767.1 | hypothetical protein | - |
| LOE13_RS19080 (LOE13_19075) | 3815212..3816396 | - | 1185 | WP_224557768.1 | site-specific integrase | - |
| LOE13_RS19090 (LOE13_19085) | 3816774..3817472 | - | 699 | WP_037931342.1 | SURF1 family protein | - |
| LOE13_RS19095 (LOE13_19090) | 3817469..3817834 | - | 366 | WP_028957811.1 | cytochrome o ubiquinol oxidase subunit IV | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 3803883..3816396 | 12513 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10254.52 Da Isoelectric Point: 5.6550
>T224603 WP_224557762.1 NZ_CP086954:3812477-3812740 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST
Download Length: 264 bp
>T224603 NZ_CP120363:c20356-19820 [Chelativorans sp. AA-79]
ATGACCCTTCCGGATTGGCGCGAGGAGCCGATCGCGAAGGCCCATGATCGCAAGGGGTTCGACTGCGGACAGCCCGAACT
CAATGATTTCCTGATGCGCTACGCACGTCAGGCGAGCGAGAGCGGCGCTTCAAAGACCTATGTCGCCGTCGACAGCGGCA
ACAGGACGACCATTCTCGGGTTCTATACCCTAAGCCCGGCGCAGATCGATTTCGAAGCCGTGCCCGACGTGGCACGCCCA
GCTGGTGGCGGCCGCCATGCCATCGGAGGATTTCGGCTTGGACGGCTGGCCGTCGCCACAGCCCATCAAGGTCACGGCCT
GGGCGGCGAACTGCTGATTGCTGCGGCACGTCGCTGCATTCGCGCCTCGACGGAGGTCGGCGGCACGCTGCTGTTCATCG
ATGCGAAGGACGAGCGGGCCGCGGCTTGGTACAGGTCCTACGGCGCCGTCACGATTCCCAAGGCGCCCCTGTCATTGGTG
CTGCCCTATTCGGTGTTCATCGCGGTGATGGAACAGGCGGGCAAGCCGATCATCTAG
ATGACCCTTCCGGATTGGCGCGAGGAGCCGATCGCGAAGGCCCATGATCGCAAGGGGTTCGACTGCGGACAGCCCGAACT
CAATGATTTCCTGATGCGCTACGCACGTCAGGCGAGCGAGAGCGGCGCTTCAAAGACCTATGTCGCCGTCGACAGCGGCA
ACAGGACGACCATTCTCGGGTTCTATACCCTAAGCCCGGCGCAGATCGATTTCGAAGCCGTGCCCGACGTGGCACGCCCA
GCTGGTGGCGGCCGCCATGCCATCGGAGGATTTCGGCTTGGACGGCTGGCCGTCGCCACAGCCCATCAAGGTCACGGCCT
GGGCGGCGAACTGCTGATTGCTGCGGCACGTCGCTGCATTCGCGCCTCGACGGAGGTCGGCGGCACGCTGCTGTTCATCG
ATGCGAAGGACGAGCGGGCCGCGGCTTGGTACAGGTCCTACGGCGCCGTCACGATTCCCAAGGCGCCCCTGTCATTGGTG
CTGCCCTATTCGGTGTTCATCGCGGTGATGGAACAGGCGGGCAAGCCGATCATCTAG
Antitoxin
Download Length: 72 a.a. Molecular weight: 8265.40 Da Isoelectric Point: 10.6538
>AT224603 WP_224557764.1 NZ_CP086954:3812727-3812942 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ
Download Length: 216 bp
>AT224603 NZ_CP120363:c20631-20353 [Chelativorans sp. AA-79]
ATGCCCAGAGCCGCCGCCGAAAACACCAGCCGCTTCCCCATGCAAATCCCGCCCGCCGACAAGGCTCGGCTGATGCGGGC
CGCCGCGCTTGAGCGCACGAGCCTCAAGGAGTTCGTGCTGCGCAATGCGCTCCAGGCCGCCGAAATCGTGATCGAGCGGG
CGGAGCGGGTCACTCTCGATGAAGAACAGACACGCTTCATGCTCGATCTGCTCGACCATCCGCCGGCGCCCAATGCGAAG
CTGCGCAAAGCTGCCCGTTCGCTCGCTGCTCGTAAATGA
ATGCCCAGAGCCGCCGCCGAAAACACCAGCCGCTTCCCCATGCAAATCCCGCCCGCCGACAAGGCTCGGCTGATGCGGGC
CGCCGCGCTTGAGCGCACGAGCCTCAAGGAGTTCGTGCTGCGCAATGCGCTCCAGGCCGCCGAAATCGTGATCGAGCGGG
CGGAGCGGGTCACTCTCGATGAAGAACAGACACGCTTCATGCTCGATCTGCTCGACCATCCGCCGGCGCCCAATGCGAAG
CTGCGCAAAGCTGCCCGTTCGCTCGCTGCTCGTAAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|