Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 31905..32466 Replicon plasmid P5
Accession NZ_CP086943
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-29

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOE15_RS21510 Protein ID WP_224557555.1
Coordinates 31905..32180 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOE15_RS21515 Protein ID WP_224557554.1
Coordinates 32173..32466 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE15_RS21495 (LOE15_21450) 27694..29010 - 1317 WP_224557560.1 lactate racemase domain-containing protein -
LOE15_RS21500 (LOE15_21455) 29027..30574 - 1548 WP_224557559.1 altronate dehydratase family protein -
LOE15_RS21505 (LOE15_21460) 30666..31436 + 771 WP_224557557.1 GntR family transcriptional regulator -
LOE15_RS21510 (LOE15_21465) 31905..32180 - 276 WP_224557555.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOE15_RS21515 (LOE15_21470) 32173..32466 - 294 WP_224557554.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOE15_RS21520 (LOE15_21475) 32537..33442 - 906 WP_224557552.1 dihydrodipicolinate synthase family protein -
LOE15_RS21525 (LOE15_21480) 33453..35192 - 1740 WP_224557550.1 L-arabinonate dehydratase -
LOE15_RS21530 (LOE15_21485) 35454..36989 + 1536 WP_224557548.1 aldehyde dehydrogenase (NADP(+)) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82227 82227


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10108.67 Da        Isoelectric Point: 4.4912

>T224593 WP_224557555.1 NZ_CP086943:c32180-31905 [Pseudosulfitobacter pseudonitzschiae]
VPDLEWKALAVADLMAIVDYISDDNPDAAISLMDDIQDKVLGLLTHPKSGRPGRVNDTRELVIRPNYIVVYAENTAAVTI
LRVLHAVQMWP

Download         Length: 276 bp

>T224593 NZ_CP120359:1877972-1878268 [Pseudomonas sp. AA-38]
ATGGAAAAGCGCAAACCCCATTTCAAGCTTGAGCTGGTGAAGCAGGCCGTAGCCGAGCAGCGTTATCGCTTCACCCGCGT
AGCCCTGGAAGGGGGCGCTGAGCTGGGTATGGGGATGGCCGACATGCTGGCCGTCATCAGTGCCCTGAGCAGCCGCGACT
TTTTCAAGAGCATGACAACCTATGCGGATCATACTACCTGGCAAGACGTTTACCGACCCGAAACCGAGTTCGGGCAGGTC
TATCTGAAGTTCACGCTGGTGGCCGATCTGCTGATCGTTTCCTTCAAGGAGAAGTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10166.59 Da        Isoelectric Point: 7.2024

>AT224593 WP_224557554.1 NZ_CP086943:c32466-32173 [Pseudosulfitobacter pseudonitzschiae]
MSAQTSMIHVRVDDQLKAKATDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTANPDAYDAWFRAKVQDALADAAPAKPH
DQVMRDARALIDGKRGA

Download         Length: 294 bp

>AT224593 NZ_CP120359:1878271-1878672 [Pseudomonas sp. AA-38]
ATGAAATGTCCAGTATGCGGCGGGGCGGAACTGGTTCACGACACCCGCGATATGCCCTTCACCTACAAGGGGCAGACCAC
TCAAATTGCCGCAGTAACGGCTGACTGGTGCGATGCCTGCGGCGAGTCCCTGACCGGGCCGGCTGAGAGCGAGCGCGTCA
TCTGTGCCATGAACGAGTTTCGTCAGCAGGTGAACGCTCGGAGCGGTAATCAGGAGCTGATTCGCAGTGTGCGCAAGCAG
TTGCGCTTGAGCCAGCGTGAAGCGGCCGAGCTGTTTGGTGGTGGCCCGAATGCGTTTTCTCGCTATGAGCGAGGCAGCAC
GGAAGCACCGCAGCCGCTGGTGCAGTTGTTCAAGATACTGGGGCGTCACCCGGAGCTGATCAACGAGCTGCGTGCAGGTT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References