Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 4742..5303 Replicon plasmid P6
Accession NZ_CP086936
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-30

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOE16_RS22155 Protein ID WP_224557555.1
Coordinates 5028..5303 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOE16_RS22150 Protein ID WP_224557554.1
Coordinates 4742..5035 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE16_RS22135 (LOE16_22130) 219..1754 - 1536 WP_224557548.1 aldehyde dehydrogenase (NADP(+)) -
LOE16_RS22140 (LOE16_22135) 2016..3755 + 1740 WP_224557550.1 L-arabinonate dehydratase -
LOE16_RS22145 (LOE16_22140) 3766..4671 + 906 WP_224557552.1 dihydrodipicolinate synthase family protein -
LOE16_RS22150 (LOE16_22145) 4742..5035 + 294 WP_224557554.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOE16_RS22155 (LOE16_22150) 5028..5303 + 276 WP_224557555.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOE16_RS22160 (LOE16_22155) 5772..6542 - 771 WP_224557557.1 GntR family transcriptional regulator -
LOE16_RS22165 (LOE16_22160) 6634..8181 + 1548 WP_224557559.1 altronate dehydratase family protein -
LOE16_RS22170 (LOE16_22165) 8198..9514 + 1317 WP_224557560.1 lactate racemase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82231 82231


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10108.67 Da        Isoelectric Point: 4.4912

>T224588 WP_224557555.1 NZ_CP086936:5028-5303 [Pseudosulfitobacter pseudonitzschiae]
VPDLEWKALAVADLMAIVDYISDDNPDAAISLMDDIQDKVLGLLTHPKSGRPGRVNDTRELVIRPNYIVVYAENTAAVTI
LRVLHAVQMWP

Download         Length: 276 bp

>T224588 NZ_CP120350:50119-50424 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTACCGCCTGTTTGTGGATGTGCAGAGCGACATCGTCGATAC
CCCTGGCCGGCGAATGGTGATCCCGCTGGCCAGTGCCCGTCTGCTGTCGGATAAGGTCTCCCGCGAACTTTATCCGGTGG
TGCATATCGGGGATGAGAGCTGGCGTCTGATGACCACGGATATGGCCAGTGTCCCGGCCTCATTCATCGGGGAAGAGGTG
GCCGAGCTCAGCCACAGGGAGAACGACATCAAAAACGCCATTAACCTGATGTTCTGGGGGATCTGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10166.59 Da        Isoelectric Point: 7.2024

>AT224588 WP_224557554.1 NZ_CP086936:4742-5035 [Pseudosulfitobacter pseudonitzschiae]
MSAQTSMIHVRVDDQLKAKATDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTANPDAYDAWFRAKVQDALADAAPAKPH
DQVMRDARALIDGKRGA

Download         Length: 294 bp

>AT224588 NZ_CP120350:49899-50117 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAAGCAGCGTATTACTGTCACCATAGACAGTGACAGCTATCAGTTACTCAAGTCCGCAGACGTGAATATCTCCGGCCT
GGTAAATACTGCCATGCAGAAGGAGGCCCGCCGTCTGCGTGCGGAACGCTGGCAGGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAGCGAACGGCTCCTTTGCAGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References