Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3211798..3212263 Replicon chromosome
Accession NZ_CP086930
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-30

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE16_RS16190 Protein ID WP_224557762.1
Coordinates 3212000..3212263 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE16_RS16185 Protein ID WP_224557764.1
Coordinates 3211798..3212013 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE16_RS16150 (LOE16_16140) 3206906..3207271 + 366 WP_028957811.1 cytochrome o ubiquinol oxidase subunit IV -
LOE16_RS16155 (LOE16_16145) 3207268..3207966 + 699 WP_037931342.1 SURF1 family protein -
LOE16_RS16165 (LOE16_16155) 3208344..3209528 + 1185 WP_224557768.1 site-specific integrase -
LOE16_RS16170 (LOE16_16160) 3209521..3210492 + 972 WP_224557767.1 hypothetical protein -
LOE16_RS16175 (LOE16_16165) 3210673..3211053 + 381 WP_224557766.1 helix-turn-helix domain-containing protein -
LOE16_RS16180 (LOE16_16170) 3211221..3211445 + 225 WP_224557765.1 hypothetical protein -
LOE16_RS16185 (LOE16_16175) 3211798..3212013 - 216 WP_224557764.1 CopG family antitoxin Antitoxin
LOE16_RS16190 (LOE16_16180) 3212000..3212263 - 264 WP_224557762.1 BrnT family toxin Toxin
LOE16_RS16195 (LOE16_16185) 3212451..3212894 + 444 WP_224557760.1 hypothetical protein -
LOE16_RS16200 (LOE16_16190) 3212987..3214096 + 1110 WP_224558030.1 IS110 family transposase -
LOE16_RS16205 (LOE16_16195) 3214322..3214810 + 489 WP_229938596.1 DEAD/DEAH box helicase family protein -
LOE16_RS16210 (LOE16_16200) 3214734..3215000 + 267 WP_229938971.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
LOE16_RS16215 (LOE16_16205) 3214997..3216547 + 1551 WP_224557015.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3209698..3220857 11159


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10254.52 Da        Isoelectric Point: 5.6550

>T224584 WP_224557762.1 NZ_CP086930:c3212263-3212000 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Download         Length: 264 bp

>T224584 NZ_CP120349:4667742-4668053 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGCATGTTATCAGCCGAAAACCGTTCAATGAAGCGATGCTCATGTATCCAAACCATGAGCTTGCTCTCACTGAGTTGCT
GAATGTTCTGGAGAAAAAAACATTCACTCAGCCTGAAGAGATGAAGCGGTATATTCCTTCACTGGATAATTTTAAGTACA
GAGATAAATGGTGGGTGATTGATGTTTCTGGTAACAGCCTGAGACTCATTTCCTACATAGATTTCAGGTTACATAAGATA
TTTGTGAAACATATCGTTTCCCATGCCGAATATGACAAACTGACCGCATACTATCGGGGTAATAAAGAATGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8265.40 Da        Isoelectric Point: 10.6538

>AT224584 WP_224557764.1 NZ_CP086930:c3212013-3211798 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT224584 NZ_CP120349:4668050-4668496 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAGAACTCATCGTCAGATGGATGCAACCAGCGCAAAAAAGATCGTTGATACCTTCAGCGATGCGGTAAAAACCGTCCC
ACTGATGGGGGAAGACCGAAATGACAATGAGTATCGCAGGGCACTAGCGCTAGTGGAGTTTCTGGTCGACCACGACGATC
TTGAAAACCCACTATTTGAATTGCTCTGTGCCCGAATCAGTGAATACGAAAAACATGCGCCGGAATTCAAATCACTCAAC
CAACACCTGGAGAAAACACCCCCTGGCGTTTCAGTATTGCGAACGCTCATGGATCAATACGGTCTCAAAGCAGCAGATCT
TGCCAACGAACTTGGTTCTAAATCGAACGTCAGCAACATCTTAAATGGCCGCAGAGCACTAACGGTTAATCATATTAAAG
CGCTTACACAACGCTTTAAACTACCAGCGGATGCCTTCATCGAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References