Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3808623..3809088 Replicon chromosome
Accession NZ_CP086886
Organism Pseudosulfitobacter pseudonitzschiae strain SC1-67

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE21_RS19020 Protein ID WP_224557762.1
Coordinates 3808623..3808886 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE21_RS19025 Protein ID WP_224557764.1
Coordinates 3808873..3809088 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE21_RS18995 (LOE21_18995) 3804340..3805890 - 1551 WP_224557015.1 restriction endonuclease subunit S -
LOE21_RS19000 (LOE21_19000) 3805887..3806183 - 297 WP_224557153.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
LOE21_RS19005 (LOE21_19005) 3806077..3806565 - 489 WP_229938596.1 DEAD/DEAH box helicase family protein -
LOE21_RS19010 (LOE21_19010) 3806791..3807899 - 1109 Protein_3751 IS110 family transposase -
LOE21_RS19015 (LOE21_19015) 3807992..3808435 - 444 WP_224557760.1 hypothetical protein -
LOE21_RS19020 (LOE21_19020) 3808623..3808886 + 264 WP_224557762.1 BrnT family toxin Toxin
LOE21_RS19025 (LOE21_19025) 3808873..3809088 + 216 WP_224557764.1 CopG family antitoxin Antitoxin
LOE21_RS19030 (LOE21_19030) 3809441..3809665 - 225 WP_224557765.1 hypothetical protein -
LOE21_RS19035 (LOE21_19035) 3809833..3810213 - 381 WP_224557766.1 helix-turn-helix domain-containing protein -
LOE21_RS19040 (LOE21_19040) 3810394..3811365 - 972 WP_224557767.1 hypothetical protein -
LOE21_RS19045 (LOE21_19045) 3811358..3812542 - 1185 WP_224557768.1 site-specific integrase -
LOE21_RS19055 (LOE21_19055) 3812920..3813618 - 699 WP_037931342.1 SURF1 family protein -
LOE21_RS19060 (LOE21_19060) 3813615..3813980 - 366 WP_028957811.1 cytochrome o ubiquinol oxidase subunit IV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3800243..3812542 12299


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10254.52 Da        Isoelectric Point: 5.6550

>T224549 WP_224557762.1 NZ_CP086886:3808623-3808886 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Download         Length: 264 bp

>T224549 NZ_CP120345:c1017838-1017311 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGATGTTTACAGACTGGCATGAGGCCGCGATAGGGAAAACCCACAATCGAATGAATTTTGATTGTGGGGATGCCGATCT
GAACCAATTCCTGCAACGCCATGCACGACAAAATCATGAGAAAGGGACAACGAAAACCTATGTTGCGCTTGATAATTCGG
ATGTTACACGTATCCACGGCTTTTACTCAGTCAGTCCTGCATCACTGATATATGCACAGGTTCCCGGCGCAATCAGCAAA
GGATTAGGGAGATACGATGTGCCAGTGTTTCGTCTGGGTCGTTTAGCCGTAGACAAATCTATGCAGGGGCAAGGGCTGGG
AGCACAACTTTTGTTATCTGCCGGAAAGCGTTGCATACAGGCGGCTTTGCAGGTCGGCGGCGTAGCCCTGCTTATTGATG
CCAAAAATAAACAGGTCTGCGACTGGTACAAAGGATTTGGCGCAGTACCATTAAACGATCAACCCCTTTCCTTGTTGCTG
TCGTTTAAAACGCTTTATGCTGCTTTATCTGCATCTGGTAGGTTATGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8265.40 Da        Isoelectric Point: 10.6538

>AT224549 WP_224557764.1 NZ_CP086886:3808873-3809088 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT224549 NZ_CP120345:c1018125-1017835 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAAAACCATGCCTCAGATAGCTATAGAATCTAACGAAAGGCTGTCGTTACGTGTATCGACGGATGCCAAAAAGTTGAT
AGTCCGCGCTGCGGCAATCCAGCAAACCAACCTGACGGATTTTGTGGTCAGTAACGTACTACCTGTCGCACAGAAGATTG
TTGATGCCGCCGAACGGGTATATCTGACGGAGCGTGATACTCAAATGATCATGGAAATTTTAGATAACCCGCCAGCGCCG
AATGAAAAGCTTCTTGCTGCTGCTTTCGCCCTGCCGGACATGAAGAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References