Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /BrnT(toxin) |
Location | 3658613..3659078 | Replicon | chromosome |
Accession | NZ_CP086854 | ||
Organism | Pseudosulfitobacter pseudonitzschiae strain SC33-25 |
Toxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | LOE30_RS18380 | Protein ID | WP_224557762.1 |
Coordinates | 3658613..3658876 (+) | Length | 88 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | - |
Locus tag | LOE30_RS18385 | Protein ID | WP_224557764.1 |
Coordinates | 3658863..3659078 (+) | Length | 72 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOE30_RS18355 (LOE30_18350) | 3654328..3655878 | - | 1551 | WP_224557015.1 | restriction endonuclease subunit S | - |
LOE30_RS18360 (LOE30_18355) | 3655875..3656171 | - | 297 | WP_224557153.1 | type I restriction-modification enzyme R subunit C-terminal domain-containing protein | - |
LOE30_RS18365 (LOE30_18360) | 3656065..3656553 | - | 489 | WP_229938596.1 | DEAD/DEAH box helicase family protein | - |
LOE30_RS18370 (LOE30_18365) | 3656779..3657889 | - | 1111 | Protein_3630 | IS110 family transposase | - |
LOE30_RS18375 (LOE30_18370) | 3657982..3658425 | - | 444 | WP_224557760.1 | hypothetical protein | - |
LOE30_RS18380 (LOE30_18375) | 3658613..3658876 | + | 264 | WP_224557762.1 | BrnT family toxin | Toxin |
LOE30_RS18385 (LOE30_18380) | 3658863..3659078 | + | 216 | WP_224557764.1 | CopG family antitoxin | Antitoxin |
LOE30_RS18390 (LOE30_18385) | 3659431..3659655 | - | 225 | WP_224557765.1 | hypothetical protein | - |
LOE30_RS18395 (LOE30_18390) | 3659823..3660203 | - | 381 | WP_224557766.1 | helix-turn-helix domain-containing protein | - |
LOE30_RS18400 (LOE30_18395) | 3660384..3661355 | - | 972 | WP_224557767.1 | hypothetical protein | - |
LOE30_RS18405 (LOE30_18400) | 3661348..3662532 | - | 1185 | WP_224557768.1 | site-specific integrase | - |
LOE30_RS18415 (LOE30_18410) | 3662910..3663608 | - | 699 | WP_037931342.1 | SURF1 family protein | - |
LOE30_RS18420 (LOE30_18415) | 3663605..3663970 | - | 366 | WP_028957811.1 | cytochrome o ubiquinol oxidase subunit IV | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10254.52 Da Isoelectric Point: 5.6550
>T224523 WP_224557762.1 NZ_CP086854:3658613-3658876 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST
Download Length: 264 bp
>T224523 NZ_CP120341:826331-826744 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA
Antitoxin
Download Length: 72 a.a. Molecular weight: 8265.40 Da Isoelectric Point: 10.6538
>AT224523 WP_224557764.1 NZ_CP086854:3658863-3659078 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ
Download Length: 216 bp
>AT224523 NZ_CP120341:826084-826350 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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