Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3658613..3659078 Replicon chromosome
Accession NZ_CP086854
Organism Pseudosulfitobacter pseudonitzschiae strain SC33-25

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE30_RS18380 Protein ID WP_224557762.1
Coordinates 3658613..3658876 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE30_RS18385 Protein ID WP_224557764.1
Coordinates 3658863..3659078 (+) Length 72 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE30_RS18355 (LOE30_18350) 3654328..3655878 - 1551 WP_224557015.1 restriction endonuclease subunit S -
LOE30_RS18360 (LOE30_18355) 3655875..3656171 - 297 WP_224557153.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
LOE30_RS18365 (LOE30_18360) 3656065..3656553 - 489 WP_229938596.1 DEAD/DEAH box helicase family protein -
LOE30_RS18370 (LOE30_18365) 3656779..3657889 - 1111 Protein_3630 IS110 family transposase -
LOE30_RS18375 (LOE30_18370) 3657982..3658425 - 444 WP_224557760.1 hypothetical protein -
LOE30_RS18380 (LOE30_18375) 3658613..3658876 + 264 WP_224557762.1 BrnT family toxin Toxin
LOE30_RS18385 (LOE30_18380) 3658863..3659078 + 216 WP_224557764.1 CopG family antitoxin Antitoxin
LOE30_RS18390 (LOE30_18385) 3659431..3659655 - 225 WP_224557765.1 hypothetical protein -
LOE30_RS18395 (LOE30_18390) 3659823..3660203 - 381 WP_224557766.1 helix-turn-helix domain-containing protein -
LOE30_RS18400 (LOE30_18395) 3660384..3661355 - 972 WP_224557767.1 hypothetical protein -
LOE30_RS18405 (LOE30_18400) 3661348..3662532 - 1185 WP_224557768.1 site-specific integrase -
LOE30_RS18415 (LOE30_18410) 3662910..3663608 - 699 WP_037931342.1 SURF1 family protein -
LOE30_RS18420 (LOE30_18415) 3663605..3663970 - 366 WP_028957811.1 cytochrome o ubiquinol oxidase subunit IV -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-80)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10254.52 Da        Isoelectric Point: 5.6550

>T224523 WP_224557762.1 NZ_CP086854:3658613-3658876 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Download         Length: 264 bp

>T224523 NZ_CP120341:826331-826744 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8265.40 Da        Isoelectric Point: 10.6538

>AT224523 WP_224557764.1 NZ_CP086854:3658863-3659078 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT224523 NZ_CP120341:826084-826350 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References