Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 534632..535097 Replicon chromosome
Accession NZ_CP086847
Organism Pseudosulfitobacter pseudonitzschiae strain SC33-87

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE31_RS02460 Protein ID WP_224557762.1
Coordinates 534834..535097 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag LOE31_RS02455 Protein ID WP_224557764.1
Coordinates 534632..534847 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE31_RS02420 (LOE31_02420) 529740..530105 + 366 WP_028957811.1 cytochrome o ubiquinol oxidase subunit IV -
LOE31_RS02425 (LOE31_02425) 530102..530800 + 699 WP_037931342.1 SURF1 family protein -
LOE31_RS02435 (LOE31_02435) 531178..532362 + 1185 WP_224557768.1 site-specific integrase -
LOE31_RS02440 (LOE31_02440) 532355..533326 + 972 WP_224557767.1 hypothetical protein -
LOE31_RS02445 (LOE31_02445) 533507..533887 + 381 WP_224557766.1 helix-turn-helix domain-containing protein -
LOE31_RS02450 (LOE31_02450) 534055..534279 + 225 WP_224557765.1 hypothetical protein -
LOE31_RS02455 (LOE31_02455) 534632..534847 - 216 WP_224557764.1 CopG family antitoxin Antitoxin
LOE31_RS02460 (LOE31_02460) 534834..535097 - 264 WP_224557762.1 BrnT family toxin Toxin
LOE31_RS02465 (LOE31_02465) 535285..535728 + 444 WP_224557760.1 hypothetical protein -
LOE31_RS02470 (LOE31_02470) 535821..536931 + 1111 Protein_483 IS110 family transposase -
LOE31_RS02475 (LOE31_02475) 537157..537645 + 489 WP_229938596.1 DEAD/DEAH box helicase family protein -
LOE31_RS02480 (LOE31_02480) 537569..537835 + 267 WP_229938971.1 type I restriction-modification enzyme R subunit C-terminal domain-containing protein -
LOE31_RS02485 (LOE31_02485) 537832..539382 + 1551 WP_224557015.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10254.52 Da        Isoelectric Point: 5.6550

>T224515 WP_224557762.1 NZ_CP086847:c535097-534834 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Download         Length: 264 bp

>T224515 NZ_CP120339:c4216837-4216553 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTCGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8265.40 Da        Isoelectric Point: 10.6538

>AT224515 WP_224557764.1 NZ_CP086847:c534847-534632 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Download         Length: 216 bp

>AT224515 NZ_CP120339:c4217069-4216827 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCATTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References