Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 38818..39379 Replicon plasmid P7
Accession NZ_CP086846
Organism Pseudosulfitobacter pseudonitzschiae strain TC12-31

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LOE24_RS24630 Protein ID WP_224557555.1
Coordinates 39104..39379 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LOE24_RS24625 Protein ID WP_224557554.1
Coordinates 38818..39111 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE24_RS24610 (LOE24_24575) 34296..35831 - 1536 WP_224557548.1 aldehyde dehydrogenase (NADP(+)) -
LOE24_RS24615 (LOE24_24580) 36093..37831 + 1739 Protein_31 L-arabinonate dehydratase -
LOE24_RS24620 (LOE24_24585) 37842..38747 + 906 WP_224557552.1 dihydrodipicolinate synthase family protein -
LOE24_RS24625 (LOE24_24590) 38818..39111 + 294 WP_224557554.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
LOE24_RS24630 (LOE24_24595) 39104..39379 + 276 WP_224557555.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LOE24_RS24635 (LOE24_24600) 39848..40618 - 771 WP_224557557.1 GntR family transcriptional regulator -
LOE24_RS24640 (LOE24_24605) 40710..42257 + 1548 WP_224557559.1 altronate dehydratase family protein -
LOE24_RS24645 (LOE24_24610) 42274..42606 + 333 WP_229996421.1 hypothetical protein -
LOE24_RS24650 (LOE24_24615) 42603..43589 + 987 WP_229996422.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..82222 82222


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10108.67 Da        Isoelectric Point: 4.4912

>T224514 WP_224557555.1 NZ_CP086846:39104-39379 [Pseudosulfitobacter pseudonitzschiae]
VPDLEWKALAVADLMAIVDYISDDNPDAAISLMDDIQDKVLGLLTHPKSGRPGRVNDTRELVIRPNYIVVYAENTAAVTI
LRVLHAVQMWP

Download         Length: 276 bp

>T224514 NZ_CP120339:3723655-3723930 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGAATGCCTCCGGCGTTAGCGTCCGCCATATCAACAGCGAAACCTGCATGACCGCCTGTTACTCACAAATCCCCAGCCA
GCACCTTAAGGGTGACTGGCAGGAAGAAGCGGGATTTGAGACCGGGCACGGCGTCACCGTGAAGATCTCCGAGGGGTGTT
TGATCCTGATTGCAGAGACGGACGAAGTGAGGGATCTACGGAAGGAGCTTTATCAGGTGAAAAAGTCGATGAAGCATATT
AAGGCGGGGGTAAATAATGTGGTGAACGGGGATTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10166.59 Da        Isoelectric Point: 7.2024

>AT224514 WP_224557554.1 NZ_CP086846:38818-39111 [Pseudosulfitobacter pseudonitzschiae]
MSAQTSMIHVRVDDQLKAKATDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTANPDAYDAWFRAKVQDALADAAPAKPH
DQVMRDARALIDGKRGA

Download         Length: 294 bp

>AT224514 NZ_CP120339:c3723920-3723498 [Salmonella enterica subsp. enterica serovar Muenchen]
TTCACCACATTATTTACCCCCGCCTTAATATGCTTCATCGACTTTTTCACCTGATAAAGCTCCTTCCGTAGATCCCTCAC
TTCGTCCGTCTCTGCAATCAGGATCAAACACCCCTCGGAGATCTTCACGGTGACGCCGTGCCCGGTCTCAAATCCCGCTT
CTTCCTGCCAGTCACCCTTAAGGTGCTGGCTGGGGATTTGTGAGTAACAGGCGGTCATGCAGGTTTCGCTGTTGATATGG
CGGACGCTAACGCCGGAGGCATTCATATTTGCTGACTAAATAAATTCTTATTTATCCGCCGGATGCTGGCTGATTGTGGA
GCTCAGGGTGAGTGAGTATGGGCGCGACATCCTGGCACCGCGCCTCCCTCTCCCCGGCCAGCCCCGGCCGGTGATGAGCA
GCCGGCTGCCGGGGCCGTATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References