Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 142762..143436 Replicon plasmid P4
Accession NZ_CP086802
Organism Pseudosulfitobacter pseudonitzschiae strain TT37-47

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LOE37_RS21485 Protein ID WP_224557924.1
Coordinates 143014..143436 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag LOE37_RS21480 Protein ID WP_229939240.1
Coordinates 142762..143010 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE37_RS21460 (LOE37_21455) 138675..139319 + 645 WP_224557929.1 type IV secretion system protein -
LOE37_RS21465 (LOE37_21460) 139323..140054 + 732 WP_224557928.1 TrbG/VirB9 family P-type conjugative transfer protein -
LOE37_RS21470 (LOE37_21465) 140057..141514 + 1458 WP_224557927.1 TrbI/VirB10 family protein -
LOE37_RS21475 (LOE37_21470) 141625..142614 + 990 WP_224557926.1 P-type DNA transfer ATPase VirB11 -
LOE37_RS21480 (LOE37_21475) 142762..143010 + 249 WP_229939240.1 plasmid stabilization protein Antitoxin
LOE37_RS21485 (LOE37_21480) 143014..143436 + 423 WP_224557924.1 type II toxin-antitoxin system VapC family toxin Toxin
LOE37_RS21490 (LOE37_21485) 143433..146183 + 2751 WP_224557923.1 lactate dehydrogenase -
LOE37_RS21495 (LOE37_21490) 146180..147238 + 1059 WP_224557922.1 HEPN domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..157665 157665


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15255.26 Da        Isoelectric Point: 4.3767

>T224480 WP_224557924.1 NZ_CP086802:143014-143436 [Pseudosulfitobacter pseudonitzschiae]
MIILDTNVICELLRPTPEPRIEQWLSAQDGLNVYLTSISEAELRYGLANMGNGKRRAALIDAVDRILREDLAGRILPFDS
DAAQAYASIAATRRDAGRPIAQADCQIASIAHACGATVATRNTPDFEGCEIDLINPWTTE

Download         Length: 423 bp

>T224480 NZ_CP086802:143014-143436 [Pseudosulfitobacter pseudonitzschiae]
ATGATCATCCTCGATACGAATGTCATCTGCGAGCTGTTGCGCCCGACCCCGGAGCCCAGGATCGAGCAATGGCTGTCCGC
TCAAGATGGTCTAAACGTCTACCTGACCTCGATATCGGAGGCGGAGCTGCGCTATGGCCTCGCGAACATGGGGAACGGCA
AGCGCCGCGCTGCGCTGATTGACGCCGTAGACCGCATCCTGCGCGAGGACCTCGCCGGGCGCATTCTGCCCTTCGACAGC
GACGCCGCGCAGGCATACGCCTCTATCGCCGCCACTCGTCGCGACGCCGGGCGACCGATTGCCCAGGCCGATTGCCAGAT
CGCATCCATTGCCCACGCCTGTGGCGCCACCGTCGCCACACGCAATACGCCCGACTTCGAGGGTTGCGAGATTGACCTGA
TCAACCCCTGGACAACCGAATGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9206.46 Da        Isoelectric Point: 6.7281

>AT224480 WP_229939240.1 NZ_CP086802:142762-143010 [Pseudosulfitobacter pseudonitzschiae]
MASITIRNLDDDVKRRLRIRAAEHGRSMEEEAREILRQVVGDAKPNHDLAAAIRARVGPLGGVELDLPQREAMHEPPTFD
RA

Download         Length: 249 bp

>AT224480 NZ_CP086802:142762-143010 [Pseudosulfitobacter pseudonitzschiae]
ATGGCAAGCATTACGATCCGGAACCTTGACGATGACGTGAAGCGGCGCCTTCGCATCCGAGCGGCCGAGCATGGCCGTTC
GATGGAAGAGGAGGCGCGAGAGATCCTGCGCCAAGTCGTTGGCGACGCGAAGCCCAACCATGATCTTGCCGCGGCGATCC
GTGCGCGGGTTGGACCCTTGGGTGGCGTTGAACTTGACCTTCCGCAGCGTGAAGCCATGCATGAGCCGCCCACATTCGAC
CGAGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References