Detailed information of TA system TA224468

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 545192..545657
• Replicon: chromosome
• Accession: NZ_CP086790
• Organism: Pseudosulfitobacter pseudonitzschiae strain TT37-67

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LOE38_RS02550
• Protein ID: WP_224557762.1
• Coordinates: 545394..545657 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: LOE38_RS02545
• Protein ID: WP_224557764.1
• Coordinates: 545192..545407 (-)
• Length: 72 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LOE38_RS02510 (LOE38_02510)	540300..540665	+	366	WP_028957811.1	cytochrome o ubiquinol oxidase subunit IV	-
LOE38_RS02515 (LOE38_02515)	540662..541360	+	699	WP_037931342.1	SURF1 family protein	-
LOE38_RS02525 (LOE38_02525)	541738..542922	+	1185	WP_224557768.1	site-specific integrase	-
LOE38_RS02530 (LOE38_02530)	542915..543886	+	972	WP_224557767.1	hypothetical protein	-
LOE38_RS02535 (LOE38_02535)	544067..544447	+	381	WP_224557766.1	helix-turn-helix domain-containing protein	-
LOE38_RS02540 (LOE38_02540)	544615..544839	+	225	WP_224557765.1	hypothetical protein	-
LOE38_RS02545 (LOE38_02545)	545192..545407	-	216	WP_224557764.1	CopG family antitoxin	Antitoxin
LOE38_RS02550 (LOE38_02550)	545394..545657	-	264	WP_224557762.1	BrnT family toxin	Toxin
LOE38_RS02555 (LOE38_02555)	545845..546288	+	444	WP_224557760.1	hypothetical protein	-
LOE38_RS02560 (LOE38_02560)	546381..547490	+	1110	WP_224558030.1	IS110 family transposase	-
LOE38_RS02565 (LOE38_02565)	547716..548204	+	489	WP_229938596.1	DEAD/DEAH box helicase family protein	-
LOE38_RS02570 (LOE38_02570)	548128..548394	+	267	WP_229938971.1	type I restriction-modification enzyme R subunit C-terminal domain-containing protein	-
LOE38_RS02575 (LOE38_02575)	548391..549941	+	1551	WP_224557015.1	restriction endonuclease subunit S	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	543092..554251	11159

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10254.52 Da
• Isoelectric Point: 5.6550

>T224468 WP_224557762.1 NZ_CP086790:c545657-545394 [Pseudosulfitobacter pseudonitzschiae]
MKFEYDPDKSAGNKAKHGIDFDEAQALWEDPWLLEAPARTDDEPRFFAIGMIKERHWSAVCTYRGDIIRIISVRRARKQE
IEHYEST

Nucleotide

• Length: 264 bp

>T224468 NZ_CP120333:854962-855375 [Salmonella enterica subsp. enterica serovar Muenchen]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTAATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGTTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA

Antitoxin

Protein

• Length: 72 a.a.
• Molecular weight: 8265.40 Da
• Isoelectric Point: 10.6538

>AT224468 WP_224557764.1 NZ_CP086790:c545407-545192 [Pseudosulfitobacter pseudonitzschiae]
MKAREFDQKFDTGENVSDLVDWSKARRTNTQTKRVNVDFPSWVVSGLDQKAKQLGVTRQSLIKLWIAERLQ

Nucleotide

• Length: 216 bp

>AT224468 NZ_CP120333:854715-854981 [Salmonella enterica subsp. enterica serovar Muenchen]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA