Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1973437..1973582 Replicon chromosome
Accession NZ_CP086724
Organism Klebsiella pneumoniae strain KP_3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1973473..1973575 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1973437..1973582 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOQ45_RS09480 1968567..1970627 + 2061 WP_004151449.1 oligopeptidase B -
LOQ45_RS09485 1970631..1971290 - 660 WP_002911407.1 exodeoxyribonuclease X -
LOQ45_RS09490 1971369..1971599 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LOQ45_RS09495 1971712..1972086 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LOQ45_RS09500 1972090..1972959 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
LOQ45_RS09505 1972976..1973314 + 339 WP_002911404.1 YebY family protein -
- 1973437..1973582 - 146 - - Antitoxin
- 1973473..1973575 + 103 - - Toxin
LOQ45_RS09510 1973950..1974093 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LOQ45_RS09515 1974198..1975166 - 969 WP_014907334.1 VirK/YbjX family protein -
LOQ45_RS09520 1975323..1975976 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
LOQ45_RS09525 1975973..1976164 - 192 WP_002911395.1 YebW family protein -
LOQ45_RS09530 1976262..1976501 - 240 WP_002911393.1 YebV family protein -
LOQ45_RS09535 1976617..1978050 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T224376 NZ_CP086724:1973473-1973575 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT224376 NZ_CP086724:c1973582-1973437 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References