Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4180019..4180290 Replicon chromosome
Accession NZ_CP086678
Organism Escherichia coli strain EFF60

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4180149..4180252 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4180019..4180290 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LMF34_RS19935 4176574..4177236 - 663 WP_000944256.1 exodeoxyribonuclease X -
LMF34_RS19940 4177260..4177916 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LMF34_RS19945 4178018..4178248 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LMF34_RS19950 4178387..4178761 + 375 WP_000204705.1 CopC domain-containing protein YobA -
LMF34_RS19955 4178765..4179637 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
LMF34_RS19960 4179650..4179991 + 342 WP_001520705.1 YebY family protein -
- 4180019..4180290 - 272 - - Antitoxin
- 4180149..4180252 + 104 - - Toxin
LMF34_RS19965 4180387..4181043 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
LMF34_RS19970 4181044..4181235 - 192 WP_001296140.1 YebW family protein -
LMF34_RS19975 4181340..4181576 - 237 WP_001295499.1 YebV family protein -
LMF34_RS19980 4181694..4183133 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224356 NZ_CP086678:4180149-4180252 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224356 NZ_CP086678:c4180290-4180019 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References