Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 951498..951769 Replicon chromosome
Accession NZ_CP086662
Organism Escherichia coli strain E2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 951536..951639 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 951498..951769 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOE88_RS04610 948655..950094 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LOE88_RS04615 950212..950448 + 237 WP_001295499.1 YebV family protein -
LOE88_RS04620 950553..950744 + 192 WP_001296140.1 YebW family protein -
LOE88_RS04625 950745..951401 - 657 WP_000812712.1 protein-serine/threonine phosphatase -
- 951498..951769 + 272 - - Antitoxin
- 951536..951639 - 104 - - Toxin
LOE88_RS04630 951797..952138 - 342 WP_000976472.1 YebY family protein -
LOE88_RS04635 952151..953023 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LOE88_RS04640 953027..953401 - 375 WP_000204700.1 CopC domain-containing protein YobA -
LOE88_RS04645 953540..953770 + 231 WP_000916763.1 DNA polymerase III subunit theta -
LOE88_RS04650 953872..954528 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LOE88_RS04655 954552..955214 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224296 NZ_CP086662:c951639-951536 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224296 NZ_CP086662:951498-951769 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References