Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 878649..879423 Replicon chromosome
Accession NZ_CP086654
Organism Staphylococcus ratti strain CCM 9025

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag LN051_RS04225 Protein ID WP_229293317.1
Coordinates 879268..879423 (+) Length 52 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag LN051_RS04220 Protein ID WP_229293316.1
Coordinates 878649..879248 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN051_RS04200 (LN051_04200) 874370..875428 + 1059 WP_229293312.1 PTS transporter subunit IIC -
LN051_RS04205 (LN051_04205) 875841..876974 + 1134 WP_229293313.1 tRNA epoxyqueuosine(34) reductase QueG -
LN051_RS04210 (LN051_04210) 876971..877441 + 471 WP_229293314.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
LN051_RS04215 (LN051_04215) 877461..878630 + 1170 WP_229293315.1 N-acetylglucosamine-6-phosphate deacetylase -
LN051_RS04220 (LN051_04220) 878649..879248 + 600 WP_229293316.1 glucosamine-6-phosphate isomerase Antitoxin
LN051_RS04225 (LN051_04225) 879268..879423 + 156 WP_229293317.1 SAS053 family protein Toxin
LN051_RS04230 (LN051_04230) 879560..879979 + 420 WP_229293318.1 hypothetical protein -
LN051_RS04235 (LN051_04235) 880119..881504 + 1386 WP_229293319.1 class II fumarate hydratase -
LN051_RS04240 (LN051_04240) 881524..883050 + 1527 WP_229293320.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(135-197)


Sequences

Toxin        


Download         Length: 52 a.a.        Molecular weight: 6020.36 Da        Isoelectric Point: 3.9110

>T224283 WP_229293317.1 NZ_CP086654:879268-879423 [Staphylococcus ratti]
MTEDKHIDHENEMVDDFDDLVDLGKEMEQISEANDQEKFDQSHDPNVRSDK

Download         Length: 156 bp

>T224283 NZ_CP119980:c3655579-3655166 [Salmonella enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTTCTGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22391.33 Da        Isoelectric Point: 5.9458

>AT224283 WP_229293316.1 NZ_CP086654:878649-879248 [Staphylococcus ratti]
MAMNFKVFKNKDTAAIYTADIIRKQFNNNPTTIAGFHLSNEDAPVLDYLKRNVDDHAVDFSQIHILDYDKNASYFKALGV
PEKQIHEIPEDDDVEKFIEHKAKTKDNKGKLTLQVVSIDKKGEFGVPVNNGLKPAREIFVVVTGSDKADIVKKLYEDNGN
TSFIPSSLKTHRMVNIVLDEAAAQGLPDDVREYFTSLYA

Download         Length: 600 bp

>AT224283 NZ_CP119980:c3655826-3655560 [Salmonella enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References