Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) TsdAT/-
Location 727141..727667 Replicon chromosome
Accession NZ_CP086654
Organism Staphylococcus ratti strain CCM 9025

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag LN051_RS03360 Protein ID WP_229293189.1
Coordinates 727443..727667 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag LN051_RS03355 Protein ID WP_229293188.1
Coordinates 727141..727428 (+) Length 96 a.a.

Genomic Context


LN051_RS03330LN051_RS03335LN051_RS03355LN051_RS03360LN051_RS03365LN051_RS03370LN051_RS03375LN051_RS03340LN051_RS03345LN051_RS03350LN051_RS03380
Location: 722526..723164 (639 bp)
Type: Others
Protein ID: WP_229293184.1
Location: 723253..724119 (867 bp)
Type: Others
Protein ID: WP_229293185.1
Location: 727141..727428 (288 bp)
Type: Antitoxin
Protein ID: WP_229293188.1
Location: 727443..727667 (225 bp)
Type: Toxin
Protein ID: WP_229293189.1
Location: 727669..727872 (204 bp)
Type: Others
Protein ID: WP_229293190.1
Location: 727982..730171 (2190 bp)
Type: Others
Protein ID: WP_229293191.1
Location: 730256..730396 (141 bp)
Type: Others
Protein ID: WP_086375151.1
Location: 724498..724698 (201 bp)
Type: Others
Protein ID: Protein_656
Location: 724870..725502 (633 bp)
Type: Others
Protein ID: WP_229293186.1
Location: 725515..727005 (1491 bp)
Type: Others
Protein ID: WP_229293187.1
Location: 730549..731763 (1215 bp)
Type: Others
Protein ID: WP_229293192.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LN051_RS03330 (LN051_03330)722526..723164+639WP_229293184.1thiamine phosphate synthase-
LN051_RS03335 (LN051_03335)723253..724119+867WP_229293185.1membrane protein insertase YidC-
LN051_RS03340 (LN051_03340)724498..724698-201Protein_656transposase-
LN051_RS03345 (LN051_03345)724870..725502-633WP_229293186.1HD domain-containing protein-
LN051_RS03350 (LN051_03350)725515..727005-1491WP_229293187.1cardiolipin synthase-
LN051_RS03355 (LN051_03355)727141..727428+288WP_229293188.1copper-sensing transcriptional repressor CsoRAntitoxin
LN051_RS03360 (LN051_03360)727443..727667+225WP_229293189.1heavy metal-associated domain-containing proteinToxin
LN051_RS03365 (LN051_03365)727669..727872+204WP_229293190.1cation transporter-
LN051_RS03370 (LN051_03370)727982..730171+2190WP_229293191.1heavy metal translocating P-type ATPase-
LN051_RS03375 (LN051_03375)730256..730396+141WP_086375151.1Lmo0850 family protein-
LN051_RS03380 (LN051_03380)730549..731763-1215WP_229293192.1FtsW/RodA/SpoVE family cell cycle protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 75 a.a.        Molecular weight: 8546.84 Da        Isoelectric Point: 4.7063

>T224281 WP_229293189.1 NZ_CP086654:727443-727667 [Staphylococcus ratti]
MYKDIVFVEGIQSDLQKENLAQRLNQMIGVKEVTIDIERQSITLLYNTPVNLNTLEKEIYDTGYKVIRTEKGAI

Download         Length: 225 bp

>T224281 NZ_CP119980:c2487278-2487175 [Salmonella enterica]
GGCAAGGCGATTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11013.61 Da        Isoelectric Point: 6.0845

>AT224281 WP_229293188.1 NZ_CP086654:727141-727428 [Staphylococcus ratti]
MEERAHHSVEIKKNLTSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATKLLDYHMKGCITQKIEEGHETE
AMEELLVTFQKLLKD

Download         Length: 288 bp

>AT224281 NZ_CP119980:2487173-2487316 [Salmonella enterica]
ATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGC
ATTAATGCAGGCTAAATCGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTG

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References