Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2374319..2374590 Replicon chromosome
Accession NZ_CP086627
Organism Escherichia coli strain RIVM_C036569

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2374449..2374552 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2374319..2374590 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN356_RS11550 2370874..2371536 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN356_RS11555 2371560..2372216 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN356_RS11560 2372318..2372548 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LN356_RS11565 2372687..2373061 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN356_RS11570 2373065..2373937 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN356_RS11575 2373950..2374291 + 342 WP_000976472.1 YebY family protein -
- 2374319..2374590 - 272 - - Antitoxin
- 2374449..2374552 + 104 - - Toxin
LN356_RS11580 2374687..2375343 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN356_RS11585 2375344..2375535 - 192 WP_001296140.1 YebW family protein -
LN356_RS11590 2375640..2375876 - 237 WP_001295499.1 YebV family protein -
LN356_RS11595 2375994..2377433 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2367009..2375876 8867


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224259 NZ_CP086627:2374449-2374552 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224259 NZ_CP086627:c2374590-2374319 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References