Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2383689..2383960 Replicon chromosome
Accession NZ_CP086624
Organism Escherichia coli strain RIVM_C037791

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2383819..2383922 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2383689..2383960 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN354_RS11675 2380244..2380906 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN354_RS11680 2380930..2381586 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN354_RS11685 2381688..2381918 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LN354_RS11690 2382057..2382431 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN354_RS11695 2382435..2383307 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN354_RS11700 2383320..2383661 + 342 WP_000976472.1 YebY family protein -
- 2383689..2383960 - 272 - - Antitoxin
- 2383819..2383922 + 104 - - Toxin
LN354_RS11705 2384057..2384713 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN354_RS11710 2384714..2384905 - 192 WP_001296140.1 YebW family protein -
LN354_RS11715 2385010..2385246 - 237 WP_001295499.1 YebV family protein -
LN354_RS11720 2385364..2386803 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2311119..2399800 88681


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224178 NZ_CP086624:2383819-2383922 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224178 NZ_CP086624:c2383960-2383689 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References