Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2419297..2419568 Replicon chromosome
Accession NZ_CP086623
Organism Escherichia coli strain RIVM_C037794

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2419427..2419530 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2419297..2419568 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN358_RS11905 2415852..2416514 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN358_RS11910 2416538..2417194 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN358_RS11915 2417296..2417526 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LN358_RS11920 2417665..2418039 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN358_RS11925 2418043..2418915 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN358_RS11930 2418928..2419269 + 342 WP_000976472.1 YebY family protein -
- 2419297..2419568 - 272 - - Antitoxin
- 2419427..2419530 + 104 - - Toxin
LN358_RS11935 2419665..2420321 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN358_RS11940 2420322..2420513 - 192 WP_001296140.1 YebW family protein -
LN358_RS11945 2420618..2420854 - 237 WP_001295499.1 YebV family protein -
LN358_RS11950 2420972..2422411 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2346727..2435408 88681


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224151 NZ_CP086623:2419427-2419530 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224151 NZ_CP086623:c2419568-2419297 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References