Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2418452..2418723 Replicon chromosome
Accession NZ_CP086620
Organism Escherichia coli strain RIVM_C039205

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2418582..2418685 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2418452..2418723 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LN351_RS11900 2415007..2415669 - 663 WP_000944256.1 exodeoxyribonuclease X -
LN351_RS11905 2415693..2416349 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
LN351_RS11910 2416451..2416681 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LN351_RS11915 2416820..2417194 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LN351_RS11920 2417198..2418070 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
LN351_RS11925 2418083..2418424 + 342 WP_000976472.1 YebY family protein -
- 2418452..2418723 - 272 - - Antitoxin
- 2418582..2418685 + 104 - - Toxin
LN351_RS11930 2418820..2419476 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
LN351_RS11935 2419477..2419668 - 192 WP_001296140.1 YebW family protein -
LN351_RS11940 2419773..2420009 - 237 WP_001295499.1 YebV family protein -
LN351_RS11945 2420127..2421566 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2345882..2434563 88681


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T224092 NZ_CP086620:2418582-2418685 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT224092 NZ_CP086620:c2418723-2418452 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References