Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025131..2025402 Replicon chromosome
Accession NZ_CP086526
Organism Escherichia coli strain Ec-042-T20-MAC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025261..2025364 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025131..2025402 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN58_RS09760 2021686..2022348 - 663 WP_000944256.1 exodeoxyribonuclease X -
LNN58_RS09765 2022372..2023028 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LNN58_RS09770 2023130..2023360 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LNN58_RS09775 2023499..2023873 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LNN58_RS09780 2023877..2024749 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LNN58_RS09785 2024762..2025103 + 342 WP_000976492.1 YebY family protein -
- 2025131..2025402 - 272 - - Antitoxin
- 2025261..2025364 + 104 - - Toxin
LNN58_RS09790 2025499..2026155 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LNN58_RS09795 2026156..2026347 - 192 WP_001296140.1 YebW family protein -
LNN58_RS09800 2026452..2026688 - 237 WP_001295499.1 YebV family protein -
LNN58_RS09805 2026806..2028245 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223696 NZ_CP086526:2025261-2025364 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223696 NZ_CP086526:c2025402-2025131 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References