Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2025117..2025388 Replicon chromosome
Accession NZ_CP086520
Organism Escherichia coli strain Ec-042-T20-ESBL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2025247..2025350 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2025117..2025388 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN45_RS09745 2021672..2022334 - 663 WP_000944256.1 exodeoxyribonuclease X -
LNN45_RS09750 2022358..2023014 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LNN45_RS09755 2023116..2023346 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LNN45_RS09760 2023485..2023859 + 375 WP_000204699.1 CopC domain-containing protein YobA -
LNN45_RS09765 2023863..2024735 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
LNN45_RS09770 2024748..2025089 + 342 WP_000976492.1 YebY family protein -
- 2025117..2025388 - 272 - - Antitoxin
- 2025247..2025350 + 104 - - Toxin
LNN45_RS09775 2025485..2026141 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LNN45_RS09780 2026142..2026333 - 192 WP_001296140.1 YebW family protein -
LNN45_RS09785 2026438..2026674 - 237 WP_001295499.1 YebV family protein -
LNN45_RS09790 2026792..2028231 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223670 NZ_CP086520:2025247-2025350 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223670 NZ_CP086520:c2025388-2025117 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References