Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144285..2144556 Replicon chromosome
Accession NZ_CP086510
Organism Escherichia coli strain Ec-050-T0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144415..2144518 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144285..2144556 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN50_RS10255 2140840..2141502 - 663 WP_000944256.1 exodeoxyribonuclease X -
LNN50_RS10260 2141526..2142182 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
LNN50_RS10265 2142284..2142514 - 231 WP_000916763.1 DNA polymerase III subunit theta -
LNN50_RS10270 2142653..2143027 + 375 WP_000168747.1 CopC domain-containing protein YobA -
LNN50_RS10275 2143031..2143903 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
LNN50_RS10280 2143916..2144257 + 342 WP_000976476.1 YebY family protein -
- 2144285..2144556 - 272 - - Antitoxin
- 2144415..2144518 + 104 - - Toxin
LNN50_RS10285 2144653..2145309 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
LNN50_RS10290 2145310..2145501 - 192 WP_000457842.1 YebW family protein -
LNN50_RS10295 2145606..2145842 - 237 WP_001295499.1 YebV family protein -
LNN50_RS10300 2145960..2147399 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T223628 NZ_CP086510:2144415-2144518 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT223628 NZ_CP086510:c2144556-2144285 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References