Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3029338..3029483 Replicon chromosome
Accession NZ_CP086458
Organism Klebsiella pneumoniae strain MCL-2017-2-T20-MAC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3029345..3029447 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3029338..3029483 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN57_RS14845 3024870..3026303 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LNN57_RS14850 3026419..3026658 + 240 WP_002911393.1 YebV family protein -
LNN57_RS14855 3026756..3026947 + 192 WP_002911395.1 YebW family protein -
LNN57_RS14860 3026944..3027597 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
LNN57_RS14865 3027754..3028722 + 969 WP_004151446.1 VirK/YbjX family protein -
LNN57_RS14870 3028827..3028970 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3029338..3029483 + 146 - - Antitoxin
- 3029345..3029447 - 103 - - Toxin
LNN57_RS14875 3029606..3029944 - 339 WP_002911404.1 YebY family protein -
LNN57_RS14880 3029961..3030830 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
LNN57_RS14885 3030834..3031208 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LNN57_RS14890 3031321..3031551 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LNN57_RS14895 3031630..3032289 + 660 WP_032435029.1 exodeoxyribonuclease X -
LNN57_RS14900 3032293..3034353 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T223378 NZ_CP086458:c3029447-3029345 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT223378 NZ_CP086458:3029338-3029483 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References