Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3029343..3029488 | Replicon | chromosome |
| Accession | NZ_CP086455 | ||
| Organism | Klebsiella pneumoniae strain MCL-2017-2-T20-ESBL | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3029350..3029452 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3029343..3029488 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LNN48_RS14845 | 3024875..3026308 | + | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
| LNN48_RS14850 | 3026424..3026663 | + | 240 | WP_002911393.1 | YebV family protein | - |
| LNN48_RS14855 | 3026761..3026952 | + | 192 | WP_002911395.1 | YebW family protein | - |
| LNN48_RS14860 | 3026949..3027602 | - | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| LNN48_RS14865 | 3027759..3028727 | + | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| LNN48_RS14870 | 3028832..3028975 | + | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| - | 3029343..3029488 | + | 146 | - | - | Antitoxin |
| - | 3029350..3029452 | - | 103 | - | - | Toxin |
| LNN48_RS14875 | 3029611..3029949 | - | 339 | WP_002911404.1 | YebY family protein | - |
| LNN48_RS14880 | 3029966..3030835 | - | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| LNN48_RS14885 | 3030839..3031213 | - | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| LNN48_RS14890 | 3031326..3031556 | + | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| LNN48_RS14895 | 3031635..3032294 | + | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| LNN48_RS14900 | 3032298..3034358 | - | 2061 | WP_004148850.1 | oligopeptidase B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T223358 NZ_CP086455:c3029452-3029350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT223358 NZ_CP086455:3029343-3029488 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT