Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3029343..3029488 Replicon chromosome
Accession NZ_CP086455
Organism Klebsiella pneumoniae strain MCL-2017-2-T20-ESBL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3029350..3029452 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3029343..3029488 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN48_RS14845 3024875..3026308 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
LNN48_RS14850 3026424..3026663 + 240 WP_002911393.1 YebV family protein -
LNN48_RS14855 3026761..3026952 + 192 WP_002911395.1 YebW family protein -
LNN48_RS14860 3026949..3027602 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
LNN48_RS14865 3027759..3028727 + 969 WP_004151446.1 VirK/YbjX family protein -
LNN48_RS14870 3028832..3028975 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3029343..3029488 + 146 - - Antitoxin
- 3029350..3029452 - 103 - - Toxin
LNN48_RS14875 3029611..3029949 - 339 WP_002911404.1 YebY family protein -
LNN48_RS14880 3029966..3030835 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
LNN48_RS14885 3030839..3031213 - 375 WP_004151448.1 CopC domain-containing protein YobA -
LNN48_RS14890 3031326..3031556 + 231 WP_002911406.1 DNA polymerase III subunit theta -
LNN48_RS14895 3031635..3032294 + 660 WP_032435029.1 exodeoxyribonuclease X -
LNN48_RS14900 3032298..3034358 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T223358 NZ_CP086455:c3029452-3029350 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT223358 NZ_CP086455:3029343-3029488 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References