Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073207..2073352 Replicon chromosome
Accession NZ_CP086447
Organism Klebsiella pneumoniae strain AE-2247421-T0

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073243..2073345 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073207..2073352 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN40_RS10215 2068337..2070397 + 2061 WP_004151449.1 oligopeptidase B -
LNN40_RS10220 2070401..2071060 - 660 WP_002911407.1 exodeoxyribonuclease X -
LNN40_RS10225 2071139..2071369 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LNN40_RS10230 2071482..2071856 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LNN40_RS10235 2071860..2072729 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
LNN40_RS10240 2072746..2073084 + 339 WP_002911404.1 YebY family protein -
- 2073207..2073352 - 146 - - Antitoxin
- 2073243..2073345 + 103 - - Toxin
LNN40_RS10245 2073720..2073863 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LNN40_RS10250 2073968..2074936 - 969 WP_004151446.1 VirK/YbjX family protein -
LNN40_RS10255 2075093..2075746 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
LNN40_RS10260 2075743..2075934 - 192 WP_002911395.1 YebW family protein -
LNN40_RS10265 2076032..2076271 - 240 WP_002911393.1 YebV family protein -
LNN40_RS10270 2076387..2077820 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T223336 NZ_CP086447:2073243-2073345 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT223336 NZ_CP086447:c2073352-2073207 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References