Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073209..2073354 Replicon chromosome
Accession NZ_CP086431
Organism Klebsiella pneumoniae strain AE-2247421-T5-ESBL

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073245..2073347 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073209..2073354 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNN54_RS10215 2068339..2070399 + 2061 WP_004151449.1 oligopeptidase B -
LNN54_RS10220 2070403..2071062 - 660 WP_002911407.1 exodeoxyribonuclease X -
LNN54_RS10225 2071141..2071371 - 231 WP_002911406.1 DNA polymerase III subunit theta -
LNN54_RS10230 2071484..2071858 + 375 WP_004151448.1 CopC domain-containing protein YobA -
LNN54_RS10235 2071862..2072731 + 870 WP_023282759.1 copper homeostasis membrane protein CopD -
LNN54_RS10240 2072748..2073086 + 339 WP_002911404.1 YebY family protein -
- 2073209..2073354 - 146 - - Antitoxin
- 2073245..2073347 + 103 - - Toxin
LNN54_RS10245 2073722..2073865 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
LNN54_RS10250 2073970..2074938 - 969 WP_004151446.1 VirK/YbjX family protein -
LNN54_RS10255 2075095..2075748 + 654 WP_032418800.1 protein-serine/threonine phosphatase -
LNN54_RS10260 2075745..2075936 - 192 WP_002911395.1 YebW family protein -
LNN54_RS10265 2076034..2076273 - 240 WP_002911393.1 YebV family protein -
LNN54_RS10270 2076389..2077822 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T223296 NZ_CP086431:2073245-2073347 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT223296 NZ_CP086431:c2073354-2073209 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References