Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2073211..2073356 | Replicon | chromosome |
| Accession | NZ_CP086416 | ||
| Organism | Klebsiella pneumoniae strain AE-2247421-T20-ESBL | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2073247..2073349 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2073211..2073356 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LNN42_RS10215 | 2068341..2070401 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| LNN42_RS10220 | 2070405..2071064 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| LNN42_RS10225 | 2071143..2071373 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| LNN42_RS10230 | 2071486..2071860 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| LNN42_RS10235 | 2071864..2072733 | + | 870 | WP_023282759.1 | copper homeostasis membrane protein CopD | - |
| LNN42_RS10240 | 2072750..2073088 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2073211..2073356 | - | 146 | - | - | Antitoxin |
| - | 2073247..2073349 | + | 103 | - | - | Toxin |
| LNN42_RS10245 | 2073724..2073867 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| LNN42_RS10250 | 2073972..2074940 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| LNN42_RS10255 | 2075097..2075750 | + | 654 | WP_032418800.1 | protein-serine/threonine phosphatase | - |
| LNN42_RS10260 | 2075747..2075938 | - | 192 | WP_002911395.1 | YebW family protein | - |
| LNN42_RS10265 | 2076036..2076275 | - | 240 | WP_002911393.1 | YebV family protein | - |
| LNN42_RS10270 | 2076391..2077824 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T223256 NZ_CP086416:2073247-2073349 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT223256 NZ_CP086416:c2073356-2073211 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
