Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | BrnTA/BrnT-BrnA |
| Location | 1616300..1616852 | Replicon | chromosome |
| Accession | NC_009667 | ||
| Organism | Ochrobactrum anthropi ATCC 49188 | ||
Toxin (Protein)
| Gene name | brnT | Uniprot ID | A6WZ45 |
| Locus tag | OANT_RS07960 | Protein ID | WP_012091587.1 |
| Coordinates | 1616592..1616852 (-) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | brnA | Uniprot ID | A6WZ44 |
| Locus tag | OANT_RS07955 | Protein ID | WP_012091586.1 |
| Coordinates | 1616300..1616605 (-) | Length | 102 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OANT_RS07890 | 1611922..1612335 | + | 414 | WP_012091579.1 | hypothetical protein | - |
| OANT_RS07895 | 1612325..1612819 | + | 495 | WP_012091580.1 | hypothetical protein | - |
| OANT_RS07900 | 1612816..1613076 | + | 261 | WP_012091581.1 | hypothetical protein | - |
| OANT_RS07905 | 1613069..1613272 | + | 204 | WP_041545065.1 | hypothetical protein | - |
| OANT_RS07910 | 1613269..1613508 | + | 240 | WP_012091582.1 | hypothetical protein | - |
| OANT_RS07915 | 1613520..1613978 | + | 459 | WP_012091583.1 | deoxycytidine triphosphate deaminase | - |
| OANT_RS07925 | 1614364..1614609 | - | 246 | WP_049768397.1 | DUF982 domain-containing protein | - |
| OANT_RS07930 | 1614688..1614903 | - | 216 | WP_041545071.1 | hypothetical protein | - |
| OANT_RS07935 | 1614947..1615624 | - | 678 | WP_012091585.1 | SOS response-associated peptidase | - |
| OANT_RS07940 | 1615631..1615864 | - | 234 | WP_041545073.1 | hypothetical protein | - |
| OANT_RS07945 | 1615866..1616093 | - | 228 | WP_041545074.1 | hypothetical protein | - |
| OANT_RS07955 | 1616300..1616605 | - | 306 | WP_012091586.1 | BrnA antitoxin family protein | Antitoxin |
| OANT_RS07960 | 1616592..1616852 | - | 261 | WP_012091587.1 | BrnT family toxin | Toxin |
| OANT_RS25055 | 1616955..1617473 | - | 519 | WP_012091588.1 | hypothetical protein | - |
| OANT_RS07970 | 1617502..1619772 | - | 2271 | WP_012091589.1 | AAA family ATPase | - |
| OANT_RS07975 | 1619774..1620085 | - | 312 | WP_012091590.1 | hypothetical protein | - |
| OANT_RS07980 | 1620099..1620554 | - | 456 | WP_012091591.1 | single-stranded DNA-binding protein | - |
| OANT_RS25550 | 1620566..1620832 | - | 267 | WP_012091592.1 | hypothetical protein | - |
| OANT_RS26355 | 1620825..1621031 | + | 207 | WP_125334435.1 | hypothetical protein | - |
| OANT_RS07990 | 1621153..1621704 | - | 552 | WP_041545080.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1574899..1638532 | 63633 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 87 a.a. Molecular weight: 9942.49 Da Isoelectric Point: 8.5409
>T22321 WP_012091587.1 NC_009667:c1616852-1616592 [Ochrobactrum anthropi ATCC 49188]
MKIIWDETKRLTNLEKHKGFDFADLTTEFFDNAAIYPAKQGRLMAVGEFRGETIIATIFVLLGTEALSVISMRRASRKER
KLYDEQ
MKIIWDETKRLTNLEKHKGFDFADLTTEFFDNAAIYPAKQGRLMAVGEFRGETIIATIFVLLGTEALSVISMRRASRKER
KLYDEQ
Download Length: 261 bp
>T22321 NC_009667:c1616852-1616592 [Ochrobactrum anthropi ATCC 49188]
ATGAAGATCATTTGGGACGAAACGAAGCGGCTTACGAACCTTGAAAAACACAAGGGGTTTGACTTTGCCGACCTGACCAC
AGAATTTTTTGACAACGCGGCGATTTACCCCGCGAAGCAAGGCCGCTTGATGGCGGTCGGAGAGTTCCGGGGCGAGACAA
TTATAGCGACGATTTTCGTCCTACTTGGAACTGAGGCGCTTTCGGTAATTTCGATGCGCCGCGCCAGCCGGAAGGAAAGG
AAGTTATATGACGAACAATAA
ATGAAGATCATTTGGGACGAAACGAAGCGGCTTACGAACCTTGAAAAACACAAGGGGTTTGACTTTGCCGACCTGACCAC
AGAATTTTTTGACAACGCGGCGATTTACCCCGCGAAGCAAGGCCGCTTGATGGCGGTCGGAGAGTTCCGGGGCGAGACAA
TTATAGCGACGATTTTCGTCCTACTTGGAACTGAGGCGCTTTCGGTAATTTCGATGCGCCGCGCCAGCCGGAAGGAAAGG
AAGTTATATGACGAACAATAA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11220.70 Da Isoelectric Point: 10.2394
>AT22321 WP_012091586.1 NC_009667:c1616605-1616300 [Ochrobactrum anthropi ATCC 49188]
MTNNKRKAIRPLTDAEEAEIQREIAADPDAPELTDEQATQRMTFAEAVRRTRGPGKKAPKETVTLRLDPDVVEAFKADGP
GWQGRVNEALRKAKKLPNRAA
MTNNKRKAIRPLTDAEEAEIQREIAADPDAPELTDEQATQRMTFAEAVRRTRGPGKKAPKETVTLRLDPDVVEAFKADGP
GWQGRVNEALRKAKKLPNRAA
Download Length: 306 bp
>AT22321 NC_009667:c1616605-1616300 [Ochrobactrum anthropi ATCC 49188]
ATGACGAACAATAAGCGAAAGGCGATCCGACCGCTGACAGATGCGGAGGAAGCGGAAATTCAGCGGGAAATCGCCGCTGA
TCCCGACGCGCCGGAATTGACGGACGAACAGGCCACGCAGCGCATGACGTTCGCAGAGGCGGTTCGGCGCACACGTGGCC
CCGGCAAGAAAGCTCCGAAAGAAACGGTCACGCTTCGGCTCGACCCGGACGTCGTAGAAGCCTTCAAGGCAGACGGCCCC
GGCTGGCAAGGCCGGGTCAACGAAGCGCTCCGCAAGGCAAAGAAGCTTCCGAACCGGGCCGCATAG
ATGACGAACAATAAGCGAAAGGCGATCCGACCGCTGACAGATGCGGAGGAAGCGGAAATTCAGCGGGAAATCGCCGCTGA
TCCCGACGCGCCGGAATTGACGGACGAACAGGCCACGCAGCGCATGACGTTCGCAGAGGCGGTTCGGCGCACACGTGGCC
CCGGCAAGAAAGCTCCGAAAGAAACGGTCACGCTTCGGCTCGACCCGGACGTCGTAGAAGCCTTCAAGGCAGACGGCCCC
GGCTGGCAAGGCCGGGTCAACGAAGCGCTCCGCAAGGCAAAGAAGCTTCCGAACCGGGCCGCATAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|