Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2370533..2372249 Replicon chromosome
Accession NC_009665
Organism Shewanella baltica OS185

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag SHEW185_RS10255 Protein ID WP_012089075.1
Coordinates 2371314..2372249 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag SHEW185_RS10250 Protein ID WP_012089074.1
Coordinates 2370533..2371321 (+) Length 263 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEW185_RS10225 2366703..2367647 + 945 WP_012089069.1 viperin family antiviral radical SAM protein -
SHEW185_RS10230 2367657..2367977 + 321 WP_012089070.1 hypothetical protein -
SHEW185_RS10235 2368352..2369140 + 789 WP_012089071.1 trypsin-like serine protease -
SHEW185_RS10240 2369252..2369632 + 381 WP_012089072.1 DUF952 domain-containing protein -
SHEW185_RS10245 2369880..2370278 - 399 WP_012089073.1 hypothetical protein -
SHEW185_RS10250 2370533..2371321 + 789 WP_012089074.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
SHEW185_RS10255 2371314..2372249 + 936 WP_012089075.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SHEW185_RS10260 2372369..2372779 - 411 WP_012089076.1 hypothetical protein -
SHEW185_RS10265 2372816..2373073 - 258 WP_012089077.1 hypothetical protein -
SHEW185_RS10270 2374042..2375358 + 1317 WP_012089078.1 hypothetical protein -
SHEW185_RS10275 2375378..2375908 + 531 WP_006087243.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-266)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-97)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35365.13 Da        Isoelectric Point: 6.7660

>T22318 WP_012089075.1 NC_009665:2371314-2372249 [Shewanella baltica OS185]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAQINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGISREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELVLTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLFNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Download         Length: 936 bp

>T22318 NC_009665:2371314-2372249 [Shewanella baltica OS185]
ATGAATAAGTCATCGATATACTACCAGCAAGTGACCTTGCTTATTCGGATGCTGCCGCTCGTCGCCCAAGAGAAGGTATT
TGCCCTAAAGGGCGGTACGGCTATCAACCTATTTGTACGCAACTTCCCACGCTTATCGGTCGATATCGATTTGGCTTATC
TTCCTTTGGAGCCAAGGGAACAAGCGCTACAAAGTGTGAAGGAAGCGCTTGGTCGTTTGACTGCGCAGATCAATCTACAA
CCGAACCTTAGTGCAGTATTTCAAGACAATAAATATGATGAGCTCAGGGTTGTCGTGACAAGTGATAGAGTCACAATAAA
AATTGAAGTCTCTCCTGTTGCGAGAGGTACGCTACACAAAGCGGTATTAATGCCAGTCGTTGAGTTAGTTGAAGAAGAAT
TTGGGTATGCAGAGATCCCCGTCGTAAGCCTGCCTGATCTATACGGTGGTAAGTTATGTGCAGCGATGGATAGGCAGCAC
CCAAGGGATCTTTTCGATGTGAAAATGCTGCTGGCGGAAGAGGGGATCAGTCGAGAGATTTTAGTCGGCTTTCTCACTTA
TACACTTAGCCATCCAAGGCCCATTAATGAAGTGATGTCTCCACGCTGGAAACCGCTTGATGAAAGCTTTCAAACTGAAT
TCAATGGAATGACGACAAAGCCGATTAAACTCGATGAGCTGGTTTTAACTCGCTCAGAAATGCTGACAGCGTTGCAGCAT
CACTTTACTGCAAAAGACAGAGACTTTTTATTATCTTTTAAACAGGGTCAGCCTGATTGGTCATTGTTTGATGAACCGAG
CGTCGCGGCACTACCTGCGGTGAGATGGAAGCTATTCAATATCCAGAACCTAGCGAAAAACAAATCCAAGCATCAAGAAC
AACTCATTAAACTGGCTGATGTATTGGAAACGTGGGTTGCAGGTCGGATACTGTAA

Antitoxin


Download         Length: 263 a.a.        Molecular weight: 29810.92 Da        Isoelectric Point: 9.5345

>AT22318 WP_012089074.1 NC_009665:2370533-2371321 [Shewanella baltica OS185]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKQALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRKIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDGRYQITVPASFIKTAENQYE

Download         Length: 789 bp

>AT22318 NC_009665:2370533-2371321 [Shewanella baltica OS185]
ATGTCATCAAAAATAAACTGGCTGATTAATCATACGAGTCCTGGTGCGGTAGTGCTTCAGTCGTGGTTGACACAAAATGA
GATCAGCTCATCTTTGGTGAGAAAATATGTGCAGAGTGGTTGGTTGTACAAGATAAGTGCGGGGGTTTACGTTCGTCCTG
AGTCAACAGGTAAGTTACAGCCTCATTGGGTTGAAGCGCTCAAGGCTGTGAATGAGCAGCTAAAGCTTCCTGTTCACCTT
GCGGGAGTCAGTAGCCTAACGCATCAAGGGCTTAGTCATTATCTTCAACTAAGCAGCGAGCAAGTTTGGGTTGGCTGTCA
AAGTAAGCAGGCGTTGCCAAAGTGGTTCCGCGAATTGGAGGAGCAAAATTGGCTTTTCTATACCAGTAGCAAGCTGACCC
AAACGTTGGAAAAAGACTTTATTACTATAGGGGTGAACAATAGGGAAGTTAAGGCAAGTTGTGCGGAGCTTGCAGCCTAT
GAGGTCGTCAATGCCATTGGCAAACATATCAGTTTTGAGCATGCCGCGGAGCTGTTTCAAGGGTTAGTGAATCTCAGCCC
ACGTAAAATACAGTCAATACTGAATCGAAGTGAAGCCGTACAAGCTAATCGCGTATTTCTCTTTTTAGGCCACTACTATC
AACACCAGTGGAGCAAAAGGCTAGATGAGCAGCAAATCACGCTTGGTGCGGGAAAGCGTCAGGTGGTGGCTCATGGCCGT
TACGATGGGCGGTATCAAATAACAGTGCCGGCATCATTTATTAAGACAGCAGAAAATCAATATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References