Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2244462..2246178 Replicon chromosome
Accession NC_009665
Organism Shewanella baltica OS185

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag SHEW185_RS09690 Protein ID WP_012088992.1
Coordinates 2245243..2246178 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag SHEW185_RS09685 Protein ID WP_012088990.1
Coordinates 2244462..2245250 (+) Length 263 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SHEW185_RS09670 2239642..2241852 + 2211 WP_012088986.1 amidohydrolase family protein -
SHEW185_RS09680 2242672..2243412 - 741 WP_012088988.1 transporter substrate-binding domain-containing protein -
SHEW185_RS09685 2244462..2245250 + 789 WP_012088990.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
SHEW185_RS09690 2245243..2246178 + 936 WP_012088992.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
SHEW185_RS09695 2246629..2247072 + 444 WP_012088994.1 low molecular weight phosphotyrosine protein phosphatase -
SHEW185_RS09700 2247278..2248219 - 942 WP_006081350.1 ribosome biogenesis GTPase YlqF -
SHEW185_RS09705 2248370..2249209 - 840 WP_012088996.1 isopenicillin N synthase family oxygenase -
SHEW185_RS09710 2249588..2250493 + 906 WP_012088997.1 bifunctional methionine sulfoxide reductase B/A protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-266)

Antitoxin

Transcriptional regulator AbiEi antitoxin, N-terminal domain

(1-97)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35359.17 Da        Isoelectric Point: 6.7660

>T22317 WP_012088992.1 NC_009665:2245243-2246178 [Shewanella baltica OS185]
MNKSSIYYQQVTLLIRMLPLVAQEKVFALKGGTAINLFVRNFPRLSVDIDLAYLPLEPREQALQSVKEALGRLTAQINLQ
PNLSAVFQDNKYDELRVVVTSDRVTIKIEVSPVARGTLHKAVLMPVVELVEEEFGYAEIPVVSLPDLYGGKLCAAMDRQH
PRDLFDVKMLLAEEGITREILVGFLTYTLSHPRPINEVMSPRWKPLDESFQTEFNGMTTKPIKLDELILTRSEMLTALQH
HFTAKDRDFLLSFKQGQPDWSLFDEPSVAALPAVRWKLLNIQNLAKNKSKHQEQLIKLADVLETWVAGRIL

Download         Length: 936 bp

>T22317 NC_009665:2245243-2246178 [Shewanella baltica OS185]
ATGAATAAGTCATCGATATACTACCAGCAAGTGACCTTGCTTATTCGGATGCTGCCGCTCGTCGCCCAAGAGAAGGTATT
TGCTCTAAAGGGCGGTACGGCTATCAACCTATTTGTGCGCAACTTCCCACGATTATCGGTCGATATCGATTTGGCTTATC
TTCCTTTGGAGCCAAGGGAACAAGCGCTACAAAGTGTGAAGGAAGCGCTTGGTCGTTTGACTGCGCAGATCAATCTACAA
CCGAACCTTAGTGCAGTATTTCAAGACAATAAATATGATGAGCTCAGGGTCGTCGTGACAAGTGATAGAGTGACAATAAA
AATTGAAGTCTCTCCTGTTGCGAGAGGTACGCTACACAAAGCGGTATTAATGCCAGTCGTTGAGTTAGTTGAAGAAGAAT
TTGGGTACGCAGAGATCCCCGTCGTAAGCCTGCCTGATCTATACGGTGGTAAGTTATGTGCAGCGATGGATAGACAGCAC
CCAAGGGATCTATTTGATGTGAAAATGCTGCTGGCGGAAGAGGGGATCACTCGAGAGATTTTAGTCGGCTTTCTCACTTA
TACACTTAGCCATCCAAGGCCTATTAATGAAGTGATGTCTCCACGCTGGAAACCGCTTGATGAAAGCTTTCAAACTGAAT
TCAATGGAATGACGACAAAGCCGATTAAACTCGATGAGCTTATTTTAACTCGCTCAGAAATGCTGACAGCGTTGCAGCAT
CACTTTACTGCAAAAGACAGAGACTTTTTATTATCCTTTAAACAGGGTCAGCCTGATTGGTCATTGTTTGATGAACCGAG
CGTCGCGGCACTACCTGCGGTGAGATGGAAGCTATTGAATATCCAAAACCTAGCGAAAAACAAATCCAAGCATCAAGAAC
AACTCATTAAACTGGCTGATGTATTGGAAACGTGGGTTGCAGGTCGGATACTGTAA

Antitoxin


Download         Length: 263 a.a.        Molecular weight: 29981.14 Da        Isoelectric Point: 9.5422

>AT22317 WP_012088990.1 NC_009665:2244462-2245250 [Shewanella baltica OS185]
MSSKINWLINHTSPGAVVLQSWLTQNEISSSLVRKYVQSGWLYKISAGVYVRPESTGKLQPHWVEALKAVNEQLKLPVHL
AGVSSLTHQGLSHYLQLSSEQVWVGCQSKLALPKWFRELEEQNWLFYTSSKLTQTLEKDFITIGVNNREVKASCAELAAY
EVVNAIGKHISFEHAAELFQGLVNLSPRRIQSILNRSEAVQANRVFLFLGHYYQHQWSKRLDEQQITLGAGKRQVVAHGR
YDRRYQITVPASFIKTEENQYE

Download         Length: 789 bp

>AT22317 NC_009665:2244462-2245250 [Shewanella baltica OS185]
ATGTCATCAAAAATAAACTGGCTGATTAATCATACGAGTCCTGGTGCGGTAGTGCTTCAGTCGTGGTTGACACAAAATGA
GATCAGCTCATCTTTGGTGAGAAAATATGTGCAGAGTGGTTGGTTGTACAAGATAAGTGCGGGGGTTTACGTTCGTCCTG
AGTCAACAGGTAAGTTACAGCCTCATTGGGTTGAAGCGCTCAAGGCTGTGAATGAGCAGCTAAAGCTTCCTGTTCACCTT
GCGGGAGTCAGTAGCCTAACACATCAAGGGCTTAGTCATTATCTTCAACTAAGCAGCGAGCAAGTTTGGGTTGGCTGTCA
AAGTAAGCTGGCGTTGCCAAAGTGGTTCCGCGAATTGGAGGAGCAAAACTGGCTTTTTTACACCAGTAGCAAGCTGACCC
AAACGTTAGAAAAAGACTTTATTACTATAGGGGTAAACAATAGGGAAGTTAAGGCAAGTTGTGCGGAGCTTGCAGCCTAT
GAGGTCGTCAATGCCATTGGTAAACATATCAGTTTTGAGCATGCCGCGGAGCTGTTTCAAGGGTTAGTGAATCTCAGCCC
ACGTAGAATACAGTCAATACTGAATAGAAGTGAAGCCGTACAAGCTAATCGCGTATTTCTCTTTTTAGGCCACTACTATC
AACACCAGTGGAGCAAAAGGCTAGATGAGCAGCAAATCACGCTCGGTGCGGGAAAGCGTCAGGTGGTGGCTCATGGCCGT
TACGATAGGCGGTATCAAATAACAGTGCCGGCATCGTTTATTAAGACAGAAGAAAATCAATATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References