Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hipBA/HipA-couple_hipB |
Location | 790845..792386 | Replicon | chromosome |
Accession | NC_009665 | ||
Organism | Shewanella baltica OS185 |
Toxin (Protein)
Gene name | hipA | Uniprot ID | - |
Locus tag | SHEW185_RS03350 | Protein ID | WP_012088210.1 |
Coordinates | 791085..792386 (+) | Length | 434 a.a. |
Antitoxin (Protein)
Gene name | hipB | Uniprot ID | - |
Locus tag | SHEW185_RS03345 | Protein ID | WP_006086108.1 |
Coordinates | 790845..791081 (+) | Length | 79 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SHEW185_RS03325 | 786860..787854 | - | 995 | Protein_642 | IS110 family transposase | - |
SHEW185_RS03330 | 788274..789449 | + | 1176 | WP_006086111.1 | HEAT repeat domain-containing protein | - |
SHEW185_RS03335 | 789501..789686 | - | 186 | WP_006086110.1 | hypothetical protein | - |
SHEW185_RS03340 | 789762..790001 | - | 240 | WP_006086109.1 | esterase | - |
SHEW185_RS03345 | 790845..791081 | + | 237 | WP_006086108.1 | type II toxin-antitoxin system antitoxin HipB | Antitoxin |
SHEW185_RS03350 | 791085..792386 | + | 1302 | WP_012088210.1 | HipA domain-containing protein | Toxin |
SHEW185_RS23085 | 793515..794090 | + | 576 | WP_012088211.1 | hypothetical protein | - |
SHEW185_RS03360 | 794208..794357 | + | 150 | WP_041410993.1 | 4-carboxymuconolactone decarboxylase | - |
SHEW185_RS03365 | 794438..794689 | - | 252 | WP_012088212.1 | DUF2999 family protein | - |
SHEW185_RS03370 | 794857..796353 | + | 1497 | WP_012088213.1 | ATP-binding cassette domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 434 a.a. Molecular weight: 48529.70 Da Isoelectric Point: 5.3107
>T22314 WP_012088210.1 NC_009665:791085-792386 [Shewanella baltica OS185]
MSTSKKLTLEMHLGDLMIGELSFDATTDTFAVHYTKDWQQSGFPLSPTIPLDGTASSSQISMFLVNLLPENKGLDYLIES
LGVSKGNTFALIRAIGLDTAGAVAFVPKGTLLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYN
GEEFAFAEGALSSTHIVKFEKYRHLVLNEFMTMRLAKAIGMNVANVDIVHFGDYKVLCVERFDRRYIPNAQKVLRRHIVD
SCQALGFSVSKKYERNFGSGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSG
MEPTPWYDLVSVAMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFIDGLGLPRNLLISNLTTIARRIPQAIDGVISMLPPLD
EDEASFVAHYKAQLLARCDRYFSFAADVRDVEV
MSTSKKLTLEMHLGDLMIGELSFDATTDTFAVHYTKDWQQSGFPLSPTIPLDGTASSSQISMFLVNLLPENKGLDYLIES
LGVSKGNTFALIRAIGLDTAGAVAFVPKGTLLPETQLRPIKAEEVIQRIEDPTMWPMEIWDGKPRLSVAGVQPKLNLFYN
GEEFAFAEGALSSTHIVKFEKYRHLVLNEFMTMRLAKAIGMNVANVDIVHFGDYKVLCVERFDRRYIPNAQKVLRRHIVD
SCQALGFSVSKKYERNFGSGRDVKDIREGVSFNRLFSLAAKCRNPVAAKQDMLQWALFNLLTGNADAHGKNYSFFMTPSG
MEPTPWYDLVSVAMYEDFEQQLAMAIDDEFDPNSIYAYQLAAFIDGLGLPRNLLISNLTTIARRIPQAIDGVISMLPPLD
EDEASFVAHYKAQLLARCDRYFSFAADVRDVEV
Download Length: 1302 bp
>T22314 NC_009665:791085-792386 [Shewanella baltica OS185]
ATGAGTACTTCCAAAAAGCTCACGTTAGAGATGCACCTCGGTGATTTAATGATCGGGGAGTTATCCTTTGATGCGACGAC
CGACACCTTTGCCGTACATTACACCAAAGACTGGCAACAAAGTGGATTCCCACTATCCCCAACAATTCCCTTAGATGGCA
CAGCAAGTAGCAGTCAGATATCGATGTTTTTGGTTAACTTATTACCGGAAAACAAAGGATTAGATTATCTAATTGAATCC
CTTGGCGTCTCCAAGGGAAATACCTTTGCCTTGATCCGCGCCATTGGTCTCGATACTGCAGGTGCTGTTGCTTTTGTTCC
TAAAGGGACTTTGCTGCCTGAAACACAATTACGGCCAATTAAGGCTGAAGAAGTTATTCAGCGAATTGAAGATCCCACAA
TGTGGCCGATGGAAATTTGGGACGGCAAACCTCGACTGTCGGTAGCGGGTGTACAACCTAAATTAAACCTGTTTTATAAC
GGTGAAGAATTTGCATTTGCCGAAGGCGCACTGTCATCTACCCATATTGTTAAATTCGAAAAATATCGCCATTTAGTGCT
CAATGAATTTATGACGATGCGCTTAGCCAAGGCGATTGGAATGAATGTGGCTAATGTTGATATCGTTCATTTTGGAGATT
ACAAAGTACTCTGTGTCGAACGCTTTGACCGACGTTATATACCAAATGCGCAAAAGGTATTAAGAAGACATATTGTCGAT
AGCTGCCAAGCTCTTGGTTTTAGTGTTAGCAAAAAATATGAACGTAATTTTGGTTCAGGGCGTGATGTTAAAGATATTCG
TGAAGGGGTAAGTTTTAACAGGCTCTTTAGTCTCGCAGCAAAATGCCGTAATCCAGTGGCCGCTAAGCAGGATATGTTGC
AGTGGGCGCTATTCAATTTACTGACCGGCAATGCCGATGCACACGGTAAAAACTACTCATTTTTTATGACGCCAAGCGGA
ATGGAGCCAACCCCTTGGTACGATTTGGTCAGCGTGGCTATGTATGAGGATTTTGAACAACAGCTTGCGATGGCAATTGA
TGACGAATTTGATCCAAATAGCATTTACGCGTATCAATTGGCTGCATTTATTGATGGCTTAGGTTTACCAAGAAATTTAT
TAATCAGTAACTTAACGACAATAGCGCGAAGAATACCGCAGGCAATAGATGGTGTGATTTCAATGCTCCCGCCCCTTGAT
GAAGATGAAGCATCATTTGTGGCTCATTACAAAGCGCAGTTGCTGGCGAGATGTGATCGTTACTTTAGTTTTGCCGCCGA
TGTCAGGGATGTGGAAGTGTAG
ATGAGTACTTCCAAAAAGCTCACGTTAGAGATGCACCTCGGTGATTTAATGATCGGGGAGTTATCCTTTGATGCGACGAC
CGACACCTTTGCCGTACATTACACCAAAGACTGGCAACAAAGTGGATTCCCACTATCCCCAACAATTCCCTTAGATGGCA
CAGCAAGTAGCAGTCAGATATCGATGTTTTTGGTTAACTTATTACCGGAAAACAAAGGATTAGATTATCTAATTGAATCC
CTTGGCGTCTCCAAGGGAAATACCTTTGCCTTGATCCGCGCCATTGGTCTCGATACTGCAGGTGCTGTTGCTTTTGTTCC
TAAAGGGACTTTGCTGCCTGAAACACAATTACGGCCAATTAAGGCTGAAGAAGTTATTCAGCGAATTGAAGATCCCACAA
TGTGGCCGATGGAAATTTGGGACGGCAAACCTCGACTGTCGGTAGCGGGTGTACAACCTAAATTAAACCTGTTTTATAAC
GGTGAAGAATTTGCATTTGCCGAAGGCGCACTGTCATCTACCCATATTGTTAAATTCGAAAAATATCGCCATTTAGTGCT
CAATGAATTTATGACGATGCGCTTAGCCAAGGCGATTGGAATGAATGTGGCTAATGTTGATATCGTTCATTTTGGAGATT
ACAAAGTACTCTGTGTCGAACGCTTTGACCGACGTTATATACCAAATGCGCAAAAGGTATTAAGAAGACATATTGTCGAT
AGCTGCCAAGCTCTTGGTTTTAGTGTTAGCAAAAAATATGAACGTAATTTTGGTTCAGGGCGTGATGTTAAAGATATTCG
TGAAGGGGTAAGTTTTAACAGGCTCTTTAGTCTCGCAGCAAAATGCCGTAATCCAGTGGCCGCTAAGCAGGATATGTTGC
AGTGGGCGCTATTCAATTTACTGACCGGCAATGCCGATGCACACGGTAAAAACTACTCATTTTTTATGACGCCAAGCGGA
ATGGAGCCAACCCCTTGGTACGATTTGGTCAGCGTGGCTATGTATGAGGATTTTGAACAACAGCTTGCGATGGCAATTGA
TGACGAATTTGATCCAAATAGCATTTACGCGTATCAATTGGCTGCATTTATTGATGGCTTAGGTTTACCAAGAAATTTAT
TAATCAGTAACTTAACGACAATAGCGCGAAGAATACCGCAGGCAATAGATGGTGTGATTTCAATGCTCCCGCCCCTTGAT
GAAGATGAAGCATCATTTGTGGCTCATTACAAAGCGCAGTTGCTGGCGAGATGTGATCGTTACTTTAGTTTTGCCGCCGA
TGTCAGGGATGTGGAAGTGTAG
Antitoxin
Download Length: 79 a.a. Molecular weight: 8574.91 Da Isoelectric Point: 7.9728
>AT22314 WP_006086108.1 NC_009665:790845-791081 [Shewanella baltica OS185]
MASRLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIEIVSAQTSDTETNGWY
MASRLNQQSLGLLIKERRKSAALTQDVAAMLCGVTKKTLIRVEKGEDVYISTVFKILDGLGIEIVSAQTSDTETNGWY
Download Length: 237 bp
>AT22314 NC_009665:790845-791081 [Shewanella baltica OS185]
ATGGCATCACGGCTAAATCAACAATCCCTCGGCTTGTTAATTAAAGAACGAAGGAAAAGTGCTGCTCTTACTCAAGACGT
GGCAGCCATGCTGTGCGGCGTAACCAAAAAAACGCTGATCCGAGTTGAAAAAGGTGAGGATGTTTATATCTCAACCGTAT
TCAAAATCCTTGATGGTCTGGGGATTGAGATCGTTTCGGCTCAAACCAGCGACACCGAAACTAACGGCTGGTATTAA
ATGGCATCACGGCTAAATCAACAATCCCTCGGCTTGTTAATTAAAGAACGAAGGAAAAGTGCTGCTCTTACTCAAGACGT
GGCAGCCATGCTGTGCGGCGTAACCAAAAAAACGCTGATCCGAGTTGAAAAAGGTGAGGATGTTTATATCTCAACCGTAT
TCAAAATCCTTGATGGTCTGGGGATTGAGATCGTTTCGGCTCAAACCAGCGACACCGAAACTAACGGCTGGTATTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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