Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1491468..1491818 Replicon chromosome
Accession NZ_CP086372
Organism Xanthomonas oryzae pv. oryzae strain GXO2001

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag LNP58_RS07125 Protein ID WP_011257368.1
Coordinates 1491468..1491602 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag LNP58_RS07130 Protein ID WP_011407410.1
Coordinates 1491666..1491818 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LNP58_RS07110 (LNP58_07105) 1488485..1489429 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
LNP58_RS07115 (LNP58_07110) 1489560..1490849 - 1290 WP_075242213.1 tryptophan--tRNA ligase -
LNP58_RS07120 (LNP58_07115) 1491018..1491227 - 210 WP_011407411.1 CsbD family protein -
LNP58_RS07125 (LNP58_07120) 1491468..1491602 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
LNP58_RS07130 (LNP58_07125) 1491666..1491818 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
LNP58_RS07135 (LNP58_07130) 1491926..1492849 - 924 WP_011407409.1 arginase -
LNP58_RS07140 (LNP58_07135) 1493171..1493389 + 219 Protein_1368 hypothetical protein -
LNP58_RS07145 (LNP58_07140) 1493381..1493836 + 456 Protein_1369 hypothetical protein -
LNP58_RS07150 (LNP58_07145) 1493833..1494375 + 543 Protein_1370 GTPase -
LNP58_RS07155 (LNP58_07150) 1494855..1495538 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T223138 WP_011257368.1 NZ_CP086372:c1491602-1491468 [Xanthomonas oryzae pv. oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T223138 NZ_CP118537:c4040814-4040530 [Salmonella enterica subsp. enterica serovar Typhi]
ATGACTTATGAACTGGAATTCGACCCGAGGGCCTTAAAAGAGTGGCATAAGCTGGGCGATACGGTGAAGGCTCAGCTTAA
GAAAAAGTTGGCTGATGTGCTATTGAACCCCAGAATCGACTCTGCCCGTTTAAACGGTCTTCCTGACTGCTATAAAATTA
AGCTTAAATCGTCCGGTTATCGTCTGGTGTACCAGGTTCGGGATGACGTTGTGATTGTGTTTGTTGTTGCGGTCGGCAAG
CGAGAACATTCAGCCGTCTATCACGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT223138 WP_011407410.1 NZ_CP086372:c1491818-1491666 [Xanthomonas oryzae pv. oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT223138 NZ_CP118537:c4041046-4040804 [Salmonella enterica subsp. enterica serovar Typhi]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCCGTGCGATTACTGTTCCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACTCTTAGCGACA
GTGAAGATGCACTGATTCAGACAGTTCGGGAGAGGCTGTCTAGTCCGCAAAAGGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References