Detailed information of TA system TA223137

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 841444..842189
• Replicon: chromosome
• Accession: NZ_CP086372
• Organism: Xanthomonas oryzae pv. oryzae strain GXO2001

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: LNP58_RS03970
• Protein ID: WP_199285672.1
• Coordinates: 841444..841773 (+)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: LNP58_RS03975
• Protein ID: WP_011407754.1
• Coordinates: 841770..842189 (+)
• Length: 140 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LNP58_RS03940 (LNP58_03940)	836575..837246	+	672	WP_011407759.1	class I SAM-dependent methyltransferase	-
LNP58_RS03950 (LNP58_03950)	837548..838339	-	792	WP_011407758.1	polysaccharide deacetylase family protein	-
LNP58_RS03955 (LNP58_03955)	838385..839311	+	927	WP_011257932.1	Grx4 family monothiol glutaredoxin	-
LNP58_RS03960 (LNP58_03960)	839643..839978	+	336	WP_011407757.1	DarT ssDNA thymidine ADP-ribosyltransferase family protein	-
LNP58_RS03965 (LNP58_03965)	840022..841341	-	1320	WP_011407756.1	IS701 family transposase	-
LNP58_RS03970 (LNP58_03970)	841444..841773	+	330	WP_199285672.1	DUF4433 domain-containing protein	Toxin
LNP58_RS03975 (LNP58_03975)	841770..842189	+	420	WP_011407754.1	macro domain-containing protein	Antitoxin
LNP58_RS03980 (LNP58_03980)	842241..843209	+	969	WP_011258802.1	IS5-like element ISXo1 family transposase	-
LNP58_RS03985 (LNP58_03985)	843344..844000	+	657	WP_075246166.1	phosphate phosphatase	-
LNP58_RS03990 (LNP58_03990)	844038..845273	-	1236	WP_011257570.1	ISL3-like element ISXoo13 family transposase	-
LNP58_RS03995 (LNP58_03995)	845575..845901	+	327	Protein_776	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	840022..845273	5251

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (3-108)

Antitoxin

• Macro domain (18-130)

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 13145.86 Da
• Isoelectric Point: 7.1160

>T223137 WP_199285672.1 NZ_CP086372:841444-841773 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Nucleotide

• Length: 330 bp

>T223137 NZ_CP118537:c3938584-3938297 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGTAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin

Protein

• Length: 140 a.a.
• Molecular weight: 15607.02 Da
• Isoelectric Point: 6.4733

>AT223137 WP_011407754.1 NZ_CP086372:841770-842189 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Nucleotide

• Length: 420 bp

>AT223137 NZ_CP118537:c3938310-3938008 [Salmonella enterica subsp. enterica serovar Typhi]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGACAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGACGTTATGGAATGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTGAATGCCATTCTGCGCGAAGCGATGCTGCGCGAGCAAAATAAGAAATAG