Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3895313..3895857 Replicon chromosome
Accession NZ_CP086370
Organism Massilia sp. HC52

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KT882_RS17405 Protein ID WP_161071302.1
Coordinates 3895582..3895857 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KT882_RS17400 Protein ID WP_161071303.1
Coordinates 3895313..3895579 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KT882_RS17370 3890477..3891502 - 1026 WP_228892728.1 DNA polymerase III subunit delta' -
KT882_RS17375 3891499..3892116 - 618 WP_228892729.1 dTMP kinase -
KT882_RS17380 3892132..3893118 - 987 WP_187358623.1 endolytic transglycosylase MltG -
KT882_RS17385 3893236..3894252 + 1017 WP_161071306.1 folate-binding protein YgfZ -
KT882_RS17390 3894254..3894544 + 291 WP_161071305.1 DUF4936 family protein -
KT882_RS17395 3894535..3895284 + 750 WP_161071304.1 NRDE family protein -
KT882_RS17400 3895313..3895579 + 267 WP_161071303.1 CopG family transcriptional regulator Antitoxin
KT882_RS17405 3895582..3895857 + 276 WP_161071302.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KT882_RS17410 3895810..3896757 - 948 WP_228892730.1 LysR family transcriptional regulator -
KT882_RS17415 3896887..3898293 + 1407 WP_228892731.1 MFS transporter -
KT882_RS17420 3898244..3898675 - 432 WP_161071299.1 GNAT family N-acetyltransferase -
KT882_RS17425 3898724..3899638 - 915 WP_161071298.1 SDR family oxidoreductase -
KT882_RS17430 3899650..3900645 - 996 WP_228892733.1 NADP-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10372.10 Da        Isoelectric Point: 10.9123

>T223133 WP_161071302.1 NZ_CP086370:3895582-3895857 [Massilia sp. HC52]
MKILWTSKAQSDLGRLYAFLAPLNPSAAARAMAQLYAAPEKLFANPRIGEQLTGFGNREVRRILVGKYELRYEIRDSAIA
IIRVRHTREQL

Download         Length: 276 bp

>T223133 NZ_CP118537:849869-850267 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCTGAAATTCATGCTTGATACCAATACTTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCACCGG
AGCGTAATTTTGCAGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTACCGAACTGGCCCGCAAGGGAACACCTGTCGGGTCTTATGACCAGATGATTGCTGGCCATGCCCGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAGTTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9782.08 Da        Isoelectric Point: 4.2404

>AT223133 WP_161071303.1 NZ_CP086370:3895313-3895579 [Massilia sp. HC52]
MNTRDTTSWTVRIPQPLAERISALASSSQIPVDSIVEQALVLWAEREDRIYQMTLEGLADVDAGRVVDHSVIKAWVEGLN
TENPLPLP

Download         Length: 267 bp

>AT223133 NZ_CP118537:849642-849869 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGCACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References