Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 3155145..3155637 Replicon chromosome
Accession NZ_CP086370
Organism Massilia sp. HC52

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag KT882_RS14105 Protein ID WP_228896263.1
Coordinates 3155145..3155327 (-) Length 61 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag KT882_RS14110 Protein ID WP_161074277.1
Coordinates 3155356..3155637 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KT882_RS14080 3150996..3151760 + 765 WP_228896257.1 ABC transporter ATP-binding protein -
KT882_RS14085 3151757..3152467 + 711 WP_228896259.1 ABC transporter ATP-binding protein -
KT882_RS14090 3152554..3153006 - 453 WP_161074280.1 thioesterase family protein -
KT882_RS14095 3153017..3154063 - 1047 WP_161074279.1 porin -
KT882_RS14100 3154212..3155135 + 924 WP_228896261.1 LysR family transcriptional regulator -
KT882_RS14105 3155145..3155327 - 183 WP_228896263.1 type II toxin-antitoxin system YafQ family toxin Toxin
KT882_RS14110 3155356..3155637 - 282 WP_161074277.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KT882_RS14115 3155714..3156391 - 678 WP_228896639.1 thiol:disulfide interchange protein DsbA/DsbL -
KT882_RS14120 3156412..3157257 - 846 WP_228896265.1 archaetidylserine decarboxylase -
KT882_RS14125 3157422..3159566 + 2145 WP_228896266.1 TonB-dependent receptor -
KT882_RS14130 3159614..3160066 + 453 WP_228896268.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-59)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(6-76)


Sequences

Toxin        


Download         Length: 61 a.a.        Molecular weight: 6708.68 Da        Isoelectric Point: 4.9080

>T223132 WP_228896263.1 NZ_CP086370:c3155327-3155145 [Massilia sp. HC52]
MLLLIAGDAPLGAEWRDHALRGPWSEYRECHIGGDFLLIYRIAGDVITFARTGTHAELLE

Download         Length: 183 bp

>T223132 NZ_CP118537:832513-832914 [Salmonella enterica subsp. enterica serovar Typhi]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCCTTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGACAG
GACTGGACGCTCTTGCGTCCTCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
AG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10518.86 Da        Isoelectric Point: 5.0965

>AT223132 WP_161074277.1 NZ_CP086370:c3155637-3155356 [Massilia sp. HC52]
VPTPASSINIQIDADLERRANEALAQVGLSMSDAVRMFLHQVATDQRFPWDLRVPNQTTRDAMKECDDIIAHHQARFIKA
EQLFADLEKSGKE

Download         Length: 282 bp

>AT223132 NZ_CP118537:832266-832532 [Salmonella enterica subsp. enterica serovar Typhi]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGATGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References