223125

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 3663772..3664556 Replicon chromosome
Accession NZ_CP086369
Organism Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag LLE50_RS16590 Protein ID WP_130621813.1
Coordinates 3664062..3664556 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag LLE50_RS16585 Protein ID WP_130621812.1
Coordinates 3663772..3664065 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE50_RS16555 (LLE50_16545) 3659843..3660250 + 408 WP_130621810.1 hypothetical protein -
LLE50_RS16560 (LLE50_16550) 3660289..3661683 + 1395 WP_130621811.1 DUF4832 domain-containing protein -
LLE50_RS16565 (LLE50_16555) 3661710..3662210 + 501 WP_103861241.1 serine acetyltransferase -
LLE50_RS16570 (LLE50_16560) 3662417..3662710 + 294 WP_125232377.1 DUF1778 domain-containing protein -
LLE50_RS16575 (LLE50_16565) 3662707..3663201 + 495 WP_116586074.1 GNAT family N-acetyltransferase -
LLE50_RS16580 (LLE50_16570) 3663263..3663433 + 171 Protein_3233 helix-turn-helix domain-containing protein -
LLE50_RS16585 (LLE50_16575) 3663772..3664065 + 294 WP_130621812.1 DUF1778 domain-containing protein Antitoxin
LLE50_RS16590 (LLE50_16580) 3664062..3664556 + 495 WP_130621813.1 GNAT family N-acetyltransferase Toxin
LLE50_RS16595 (LLE50_16585) 3664982..3666712 + 1731 WP_130621814.1 AAA family ATPase -
LLE50_RS16600 (LLE50_16590) 3666798..3667640 + 843 WP_130621815.1 DNA adenine methylase -
LLE50_RS16605 (LLE50_16595) 3667840..3668145 - 306 WP_130621816.1 type II toxin-antitoxin system toxin CcdB -
LLE50_RS16610 (LLE50_16600) 3668148..3668366 - 219 WP_038917755.1 type II toxin-antitoxin system antitoxin CcdA -
LLE50_RS16615 (LLE50_16605) 3668425..3669168 - 744 WP_130621817.1 MobC family replication-relaxation protein -
LLE50_RS16620 (LLE50_16610) 3669305..3669466 + 162 WP_161973602.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3648153..3672248 24095


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(76-143)

Antitoxin

Vibrio phage ICP1, Orf50

(3-95)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17653.50 Da        Isoelectric Point: 7.8051

>T223125 WP_130621813.1 NZ_CP086369:3664062-3664556 [Pectobacterium versatile]
MISAPEPLHAEHVLSSFCCGVESMDNWLKQRAMKNQVTGASRTFVSCDGSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDRSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI

Download         Length: 495 bp

>T223125 NZ_CP118536:c3890248-3889961 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCCGATGGAGTTTGAATGGGATGCGAACAAGGCTAAAAGCAACCTGAGGAAGCACGGTGTCCGCTTTGAGGATGCGGT
ACTGGTGTTTGACGATCCCCGACACCTGTCACGTCAGGAGCGTTATGAGAATGGAGAATATCGTTGGCAGACCCTCGGCC
TTGTTCATGGCATTGTGGTCATTCTGGTTGCTCATAGCGTTCGGTTCGAAAGTGGTTTTGAAGTTATCCGTATCATCAGC
GCTCGTAAGGCAGACAGAAAAGAGAGGAATCGTTATGAGCATGGTTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10900.41 Da        Isoelectric Point: 8.6369

>AT223125 WP_130621812.1 NZ_CP086369:3663772-3664065 [Pectobacterium versatile]
MSATHSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPEAYQEFLARLDQAPSPN
AALRETMQTPAPWEQKK

Download         Length: 294 bp

>AT223125 NZ_CP118536:c3889974-3889672 [Salmonella enterica subsp. enterica serovar Typhi]
ATGAGCATGGTTAAACATAAACGCGGCAACGCATCCGCGCTGAGTGCTCAGCATGAGGCTGAACTGAAGGCGCTGGCGAA
AAAATCAGATGATGAGATTGATTACAGCGACATTCCCGCTTCGGAGGATGGACAGTGGTCTGAAGCAGTGCGTGGTAAGT
TTTTTCGCCCGTTAAAAACTCAGGCCTCGGTGCGTATTGACGCCGACGTTATGGAATGGCTGAAACGGCCAGGAAAAGGC
TACCAGACGCGGCTGAATGCCATTCTGCGCGAAGCGATGCTGCGCGAGCAAAATAAGAAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References