Detailed information of TA system TA223123

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 3498170..3498662
• Replicon: chromosome
• Accession: NZ_CP086369
• Organism: Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: LLE50_RS15840
• Protein ID: WP_223193489.1
• Coordinates: 3498170..3498421 (-)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: LLE50_RS15845
• Protein ID: WP_105879157.1
• Coordinates: 3498411..3498662 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LLE50_RS15805 (LLE50_15795)	3493674..3494156	+	483	WP_029367525.1	GNAT family N-acetyltransferase	-
LLE50_RS15810 (LLE50_15800)	3494202..3494828	-	627	WP_103861356.1	LysE family transporter	-
LLE50_RS15815 (LLE50_15805)	3495084..3495866	-	783	WP_103861355.1	transporter substrate-binding domain-containing protein	-
LLE50_RS15820 (LLE50_15810)	3496235..3496813	-	579	WP_130621939.1	hypothetical protein	-
LLE50_RS15825 (LLE50_15815)	3497031..3497207	-	177	WP_158256803.1	hypothetical protein	-
LLE50_RS15830 (LLE50_15820)	3497473..3497757	-	285	WP_039539560.1	type II toxin-antitoxin system RelE/ParE family toxin	-
LLE50_RS15835 (LLE50_15825)	3497747..3497998	-	252	WP_005973616.1	prevent-host-death protein	-
LLE50_RS15840 (LLE50_15830)	3498170..3498421	-	252	WP_223193489.1	hypothetical protein	Toxin
LLE50_RS15845 (LLE50_15835)	3498411..3498662	-	252	WP_105879157.1	prevent-host-death protein	Antitoxin
LLE50_RS15850 (LLE50_15840)	3498792..3499262	+	471	WP_103861352.1	hypothetical protein	-
LLE50_RS15855 (LLE50_15845)	3499262..3499591	+	330	WP_223193302.1	DUF1493 family protein	-
LLE50_RS15865 (LLE50_15855)	3500264..3500746	-	483	WP_010282425.1	SsrA-binding protein SmpB	-
LLE50_RS15870 (LLE50_15860)	3500902..3501348	+	447	WP_010282427.1	type II toxin-antitoxin system RatA family toxin	-
LLE50_RS15875 (LLE50_15865)	3501329..3501619	+	291	WP_130621940.1	RnfH family protein	-
LLE50_RS15880 (LLE50_15870)	3501858..3502193	-	336	WP_011092444.1	outer membrane protein assembly factor BamE	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 10011.62 Da
• Isoelectric Point: 10.0265

>T223123 WP_223193489.1 NZ_CP086369:c3498421-3498170 [Pectobacterium versatile]
MSYKLEFEEHALKEFKKLRAPMWEQFTKKLKEILQNPHVPANRLHGMADCYKKFIKQPKTDYKRGQFSTRGYFVVQPIYQ
GDE

Nucleotide

• Length: 252 bp

>T223123 NZ_CP118536:c1390839-1390621 [Salmonella enterica subsp. enterica serovar Typhi]
ATGTCTGATAAACCATTAACTAAAACTGATTATTTGATGCGTTTACGGCGCTGTCAGACAATTGACACTCTGGAGCGCGT
CATTGAGAAAAATAAATATGAATTGTCCGACAATGAGCTGGCTGTATTTTACTCAGCTGCGGATCACCGTCTTGCAGAAT
TGACGATGAACAAACTCTACGACAAGATCCCCTCTTCAGTATGGAAATTCATTCGTTAA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9111.41 Da
• Isoelectric Point: 5.0807

>AT223123 WP_105879157.1 NZ_CP086369:c3498662-3498411 [Pectobacterium versatile]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAMLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Nucleotide

• Length: 252 bp

>AT223123 NZ_CP118536:c1391241-1390867 [Salmonella enterica subsp. enterica serovar Typhi]
ATGGACGAATACTCACCCAAAAGACATGATATAGCACAGCTTAAATTTCTTTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAAGAAAGCAACCATGGCTGGGTTAATGACCCGACCTCAGCAGTCAACCTGCAGCTCAATGAGCTGATAGAGC
ATATTGCAACTTTCGCGCTTAATTATAAAATTAAGTACAATGAAGACAATAAATTGATTGCGCAGATAGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTATGGTATTAATACGCAGGATTTGCAAAAATGGCGTAAATCGGGCAACCGCCT
GTTCCGTTGTTTCGTCAACGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA