223120

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3232323..3234021 Replicon chromosome
Accession NZ_CP086369
Organism Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag LLE50_RS14595 Protein ID WP_130621722.1
Coordinates 3232323..3233252 (-) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag LLE50_RS14600 Protein ID WP_130621723.1
Coordinates 3233239..3234021 (-) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE50_RS14565 (LLE50_14560) 3228720..3228941 + 222 Protein_2839 ATP-binding cassette domain-containing protein -
LLE50_RS14570 (LLE50_14565) 3228938..3229165 + 228 Protein_2840 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
LLE50_RS14575 (LLE50_14570) 3229269..3229838 + 570 WP_103861699.1 ribose 1,5-bisphosphokinase -
LLE50_RS14580 (LLE50_14575) 3229877..3230650 + 774 WP_130621721.1 phosphonate metabolism protein PhnP -
LLE50_RS14585 (LLE50_14580) 3230742..3231005 - 264 WP_010286385.1 DUF2798 domain-containing protein -
LLE50_RS14590 (LLE50_14585) 3231134..3232036 + 903 WP_103164620.1 LysR family transcriptional regulator -
LLE50_RS14595 (LLE50_14590) 3232323..3233252 - 930 WP_130621722.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
LLE50_RS14600 (LLE50_14595) 3233239..3234021 - 783 WP_130621723.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
LLE50_RS14605 (LLE50_14600) 3234199..3234432 - 234 WP_226313185.1 hypothetical protein -
LLE50_RS14610 (LLE50_14605) 3234484..3234945 + 462 WP_130621724.1 hypothetical protein -
LLE50_RS14615 (LLE50_14610) 3234942..3235151 + 210 WP_039491410.1 helix-turn-helix transcriptional regulator -
LLE50_RS14625 (LLE50_14620) 3235631..3236476 + 846 WP_039491409.1 AraC family transcriptional regulator -
LLE50_RS14630 (LLE50_14625) 3236512..3237102 + 591 WP_103941983.1 LysE family translocator -
LLE50_RS14635 (LLE50_14630) 3237099..3237674 - 576 WP_040030982.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-261)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35177.69 Da        Isoelectric Point: 6.2424

>T223120 WP_130621722.1 NZ_CP086369:c3233252-3232323 [Pectobacterium versatile]
MDQRDIYARQVKLLMTTLPYVAKEPCFALKGGTAINLFVQDFPRLSVDIDLVYQTFIDRDTDLIAIDDALMRITESLNGR
PGITAIRQENKADEKRIIVNTVDAQIKIEVSPVWRGLLLPPAEMPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPITELLAPNWDIARITTLYQQEFSGMTQQATSLESLLSVTILLPQAL
RSHFTAQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQHNLAALHAKNPAKFSAAVSKLEKVLEQRF

Download         Length: 930 bp

>T223120 NZ_CP118536:c790017-789619 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCTGAAATTCATGCTTGATACCAATACTTGTATTTTCACCATCAAAAATAAGCCCGAACACATCAGAGAACGCTTCAA
CCTCAATACATCCCGAATGTGTATCAGCTCCATCACCTTAATGGAGCTGATTTACGGTGCTGAAAAAAGCCTGGCACCGG
AGCGTAATTTTGCAGTCGTGGAGGGATTTATCTCCCGCCTTGAGGTTCTGGATTACGATACACAGGCAGCGATACATACC
GGTCAAATCCGTACCGAACTGGCCCGCAAGGGAACACCTGTCGGGTCTTATGACCAGATGATTGCTGGCCATGCCCGTAG
CCGCGGACTGGTCGTCGTCACAAACAATCTCCGCGAGTTTGAACGCATTCCGGGTATCCGAATCGAAGACTGGTGCTAA

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29371.64 Da        Isoelectric Point: 7.8201

>AT223120 WP_130621723.1 NZ_CP086369:c3234021-3233239 [Pectobacterium versatile]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPIRVAGLT
SIALQGYSHYTELGKPQIWLTIPAYITLPGWFAAFEKSATFVVLYTSDLSVDVMPFTTELRIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLHLLSPRKLQALLCASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIEVGAGKRQIVPGGWLEP
DYQITVPREFKSEGVEDGSA

Download         Length: 783 bp

>AT223120 NZ_CP118536:c790244-790017 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCACACAACACTTTTTTTTAGTAACCGGACCCAGGCAGTCAGATTGCCTAAATCGATATCCTTTCCGGAGGATGTGAA
ACATGTCGAAATCATTGCGGTTGGTAGAAGCAGAATCATTACTCCAGTCGGAGAATCCTGGGACAGCTGGTTCGATGGCG
AAGGCGCCAGTACTGATTTTATGAGCACCAGAGAACAACCCGCAGTACAGGAACGGGAAGGATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References