223109

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1799864..1800414 Replicon chromosome
Accession NZ_CP086369
Organism Pectobacterium versatile strain A73-S18-O15

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag LLE50_RS08140 Protein ID WP_103861886.1
Coordinates 1800106..1800414 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag LLE50_RS08135 Protein ID WP_103861885.1
Coordinates 1799864..1800103 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LLE50_RS08115 (LLE50_08110) 1795331..1795642 - 312 WP_103861881.1 AzlD domain-containing protein -
LLE50_RS08120 (LLE50_08115) 1795639..1796373 - 735 WP_103861882.1 AzlC family ABC transporter permease -
LLE50_RS08125 (LLE50_08120) 1796479..1797315 - 837 WP_103861883.1 AraC family transcriptional regulator -
LLE50_RS08130 (LLE50_08125) 1797540..1799159 - 1620 WP_103971081.1 methyl-accepting chemotaxis protein -
LLE50_RS08135 (LLE50_08130) 1799864..1800103 + 240 WP_103861885.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
LLE50_RS08140 (LLE50_08135) 1800106..1800414 + 309 WP_103861886.1 CcdB family protein Toxin
LLE50_RS08145 (LLE50_08140) 1800555..1800719 - 165 WP_039483441.1 glucose uptake inhibitor SgrT -
LLE50_RS08150 (LLE50_08145) 1800810..1802468 + 1659 WP_116362471.1 HTH-type transcriptional regulator SgrR -
LLE50_RS08155 (LLE50_08150) 1802686..1803666 + 981 WP_145963920.1 thiamine ABC transporter substrate binding subunit -
LLE50_RS08160 (LLE50_08155) 1803642..1805249 + 1608 WP_103942232.1 thiamine/thiamine pyrophosphate ABC transporter permease ThiP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-101)

Antitoxin

Post-segregation antitoxin CcdA

(9-79)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11799.66 Da        Isoelectric Point: 9.3363

>T223109 WP_103861886.1 NZ_CP086369:1800106-1800414 [Pectobacterium versatile]
MQYKVYRNNGNSNSYPYLLNIQSDIIGELHTRLVIPLFPLHKIARPPARRLTPIVTIEGNDYLIMTHEMASVRRSQLGHE
VMDAQVYRKTIKDAVDFLLDGF

Download         Length: 309 bp

>T223109 NZ_CP118528:c2836709-2836431 [Vibrio harveyi]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTCGAGTTTCTCTATGACTTCAACCCTGATGCGGC
AGAAAAAACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAACAACCTTTAATGGGTGTACAACGAGATGGCA
TCCGCGGACGATTGCTCATTATTCCTGAGATTTCGATGATTGTCTCTTATTGGGTCGAGGGCGATATCATCAGAGTTATG
CGTGTACTCCACCAGAAACAAAAATTCCCTACGGATTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9036.37 Da        Isoelectric Point: 10.0137

>AT223109 WP_103861885.1 NZ_CP086369:1799864-1800103 [Pectobacterium versatile]
MPLTSVRHKKTVSVTLEPVLLQQAREAGINLSAILTEALKREIRLSEGEKWKQQNQKALQELNRITDKHGLLSDDDRTF

Download         Length: 240 bp

>AT223109 NZ_CP118528:c2836990-2836706 [Vibrio harveyi]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGAAC
TCTAAGTGATGCTTGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCTGTTTTCGTTGAGCACCAAACTGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References