Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | /ElaA-DUF1778 |
Location | 37619..38402 | Replicon | plasmid pS18501 |
Accession | NC_009661 | ||
Organism | Shewanella baltica OS185 |
Toxin (Protein)
Gene name | - | Uniprot ID | B8EFS1 |
Locus tag | SHEW185_RS22880 | Protein ID | WP_011979514.1 |
Coordinates | 37893..38402 (+) | Length | 170 a.a. |
Antitoxin (Protein)
Gene name | - | Uniprot ID | B8EFS2 |
Locus tag | SHEW185_RS22875 | Protein ID | WP_011979513.1 |
Coordinates | 37619..37912 (+) | Length | 98 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
SHEW185_RS22850 | 34350..34805 | + | 456 | WP_011979508.1 | type II toxin-antitoxin system HicB family antitoxin | - |
SHEW185_RS22855 | 34807..35295 | + | 489 | WP_011979509.1 | hypothetical protein | - |
SHEW185_RS22860 | 35326..35547 | + | 222 | WP_011979510.1 | hypothetical protein | - |
SHEW185_RS22865 | 36223..36846 | + | 624 | WP_012589009.1 | hypothetical protein | - |
SHEW185_RS22870 | 36848..37249 | + | 402 | WP_011979512.1 | hypothetical protein | - |
SHEW185_RS22875 | 37619..37912 | + | 294 | WP_011979513.1 | DUF1778 domain-containing protein | Antitoxin |
SHEW185_RS22880 | 37893..38402 | + | 510 | WP_011979514.1 | GNAT family N-acetyltransferase | Toxin |
SHEW185_RS22885 | 38515..38742 | + | 228 | WP_011979515.1 | hypothetical protein | - |
SHEW185_RS22890 | 39317..40315 | + | 999 | WP_011979516.1 | DUF1738 domain-containing protein | - |
SHEW185_RS22895 | 40364..40663 | + | 300 | WP_011979517.1 | hypothetical protein | - |
SHEW185_RS22900 | 41221..41580 | + | 360 | WP_006087379.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..83224 | 83224 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 170 a.a. Molecular weight: 19129.15 Da Isoelectric Point: 8.3399
>T22309 WP_011979514.1 NC_009661:37893-38402 [Shewanella baltica OS185]
MKITQFDKNEHDRKSFDCGNTELNNYLKCISGQHEKKDISRTYVLTSELNPSHIKGYYSIAVAQVSLCELPTEIAKKYPS
EITCSLIGRMAVNHTCQRQGLGSILLIDAIKRIIQASSAIPIPMIIVQAKNEDARRFYSEFGFVSFPDNYLKLMMTLAHA
KAMLKEAEH
MKITQFDKNEHDRKSFDCGNTELNNYLKCISGQHEKKDISRTYVLTSELNPSHIKGYYSIAVAQVSLCELPTEIAKKYPS
EITCSLIGRMAVNHTCQRQGLGSILLIDAIKRIIQASSAIPIPMIIVQAKNEDARRFYSEFGFVSFPDNYLKLMMTLAHA
KAMLKEAEH
Download Length: 510 bp
>T22309 NC_009661:37893-38402 [Shewanella baltica OS185]
ATGAAAATTACCCAATTTGATAAAAATGAGCATGACCGTAAGAGTTTTGATTGTGGGAATACAGAGCTAAACAATTACCT
GAAATGCATTTCAGGTCAGCATGAAAAGAAAGATATTTCAAGAACATATGTTCTTACTTCAGAGTTAAATCCTTCACACA
TAAAAGGTTATTACTCTATTGCGGTAGCTCAGGTATCACTTTGTGAGTTACCAACCGAAATAGCTAAAAAATATCCATCT
GAAATAACGTGTAGCTTGATAGGTCGAATGGCTGTTAACCATACCTGTCAAAGACAAGGGCTTGGCTCAATATTGCTTAT
AGACGCAATCAAACGAATTATCCAAGCTTCCAGTGCTATCCCCATCCCTATGATTATTGTTCAAGCAAAGAACGAAGATG
CTAGACGTTTTTATAGTGAGTTTGGTTTTGTATCCTTTCCTGATAATTATTTGAAACTCATGATGACACTGGCCCATGCT
AAAGCGATGTTGAAAGAAGCCGAACATTAA
ATGAAAATTACCCAATTTGATAAAAATGAGCATGACCGTAAGAGTTTTGATTGTGGGAATACAGAGCTAAACAATTACCT
GAAATGCATTTCAGGTCAGCATGAAAAGAAAGATATTTCAAGAACATATGTTCTTACTTCAGAGTTAAATCCTTCACACA
TAAAAGGTTATTACTCTATTGCGGTAGCTCAGGTATCACTTTGTGAGTTACCAACCGAAATAGCTAAAAAATATCCATCT
GAAATAACGTGTAGCTTGATAGGTCGAATGGCTGTTAACCATACCTGTCAAAGACAAGGGCTTGGCTCAATATTGCTTAT
AGACGCAATCAAACGAATTATCCAAGCTTCCAGTGCTATCCCCATCCCTATGATTATTGTTCAAGCAAAGAACGAAGATG
CTAGACGTTTTTATAGTGAGTTTGGTTTTGTATCCTTTCCTGATAATTATTTGAAACTCATGATGACACTGGCCCATGCT
AAAGCGATGTTGAAAGAAGCCGAACATTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10811.39 Da Isoelectric Point: 10.0024
>AT22309 WP_011979513.1 NC_009661:37619-37912 [Shewanella baltica OS185]
MKSMTNERITTRVSIESKELLEKAAALAGYASINSFIANTMISEAKRLITQEHFLVLSKNDALAFVNALDAPVKSNSRFL
NAARKHKETVNNENYPI
MKSMTNERITTRVSIESKELLEKAAALAGYASINSFIANTMISEAKRLITQEHFLVLSKNDALAFVNALDAPVKSNSRFL
NAARKHKETVNNENYPI
Download Length: 294 bp
>AT22309 NC_009661:37619-37912 [Shewanella baltica OS185]
ATGAAAAGTATGACAAATGAACGCATTACCACTCGGGTAAGCATTGAGTCAAAAGAACTATTAGAGAAAGCGGCTGCGCT
CGCTGGTTATGCCAGTATTAACAGTTTTATTGCGAATACAATGATTTCAGAAGCGAAAAGATTGATCACACAAGAGCATT
TTCTGGTGTTATCAAAAAATGATGCTTTAGCTTTTGTGAACGCTTTAGATGCACCCGTTAAAAGTAACAGTCGGTTTCTT
AATGCCGCGCGTAAGCATAAGGAAACGGTAAACAATGAAAATTACCCAATTTGA
ATGAAAAGTATGACAAATGAACGCATTACCACTCGGGTAAGCATTGAGTCAAAAGAACTATTAGAGAAAGCGGCTGCGCT
CGCTGGTTATGCCAGTATTAACAGTTTTATTGCGAATACAATGATTTCAGAAGCGAAAAGATTGATCACACAAGAGCATT
TTCTGGTGTTATCAAAAAATGATGCTTTAGCTTTTGTGAACGCTTTAGATGCACCCGTTAAAAGTAACAGTCGGTTTCTT
AATGCCGCGCGTAAGCATAAGGAAACGGTAAACAATGAAAATTACCCAATTTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A9L6I1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A380BY85 |